Liu Stephen K, Ward Marshall, Montgomery Justin, Mecchella John N, Masutani Rebecca, Bartels Stephen J, Batsis John A
Section of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Innov Aging. 2017 Aug 2;1(1):igx007. doi: 10.1093/geroni/igx007. eCollection 2017 Mar 1.
To evaluate the association of the Hospital Admission Risk Profile (HARP) score with mortality after discharge in a population of hospitalized older adults.
Retrospective cohort study.
Hospitalized patients aged 70 years or older.
Patient age at the time of admission, modified Folstein Mini-Mental Status Exam score, and self-reported instrumental activities of daily living 2 weeks prior to admission were used to calculate a HARP score. The primary outcome assessed was overall mortality up to 365 days after hospital discharge. Cox proportional hazard analyses evaluated the association between HARP score and mortality adjusting for age, sex, and comorbidities associated with increased mortality.
Of the 474 patients, 165 (34.8%) had a low HARP score, 177 (37.4%) had an intermediate, and 132 (27.8%) had a high score. HARP score was not associated with differences in 30-day readmission rates. High HARP score patients had higher mortality when compared to patients with low HARP scores at all time frames (30 days: 12.9% vs 1.8%, < .05; 90 days: 19.7% vs 4.8%, < .05; 365 days: 34.8% vs 16.9%, < .05). In fully adjusted Cox proportional models, patients with high HARP scores had a 3.5 times higher odds of mortality when compared to low HARP score patients.
The HARP score is a simple and easy to use instrument that identifies patients at increased risk for mortality after hospital discharge. Early identification of patients at increased risk for mortality has the potential to help guide treatment decisions following hospital discharge and provides additional information to providers and patients for shared decision making and may help in clarifying and achieving patient and family goals of care.
评估住院老年人群中住院风险评估量表(HARP)评分与出院后死亡率之间的关联。
回顾性队列研究。
70岁及以上的住院患者。
入院时患者年龄、改良Folstein简易精神状态检查表评分以及入院前2周自我报告的工具性日常生活活动能力用于计算HARP评分。评估的主要结局是出院后365天内的全因死亡率。Cox比例风险分析评估了HARP评分与死亡率之间的关联,并对年龄、性别以及与死亡率增加相关的合并症进行了校正。
474例患者中,165例(34.8%)HARP评分为低分,177例(37.4%)为中等评分,132例(27.8%)为高分。HARP评分与30天再入院率的差异无关。在所有时间框架内,高HARP评分患者的死亡率均高于低HARP评分患者(30天:12.9%对1.8%,P<0.05;90天:19.7%对4.8%,P<0.05;365天:34.8%对16.9%,P<0.05)。在完全校正的Cox比例模型中,高HARP评分患者的死亡几率比低HARP评分患者高3.5倍。
HARP评分是一种简单易用的工具,可识别出院后死亡风险增加的患者。早期识别死亡风险增加的患者有可能帮助指导出院后的治疗决策,并为医护人员和患者提供额外信息以进行共同决策,还可能有助于明确并实现患者及家属的护理目标。