Wong Wee Ping, Coles Jan, Chambers Richard, Wu David Bin-Chia, Hassed Craig
Department of General Practice, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, VIC, Australia.
Counselling and Mental Health Programs, Campus Community Division, Monash University, VIC, Australia.
J Alzheimers Dis Rep. 2017 Dec 2;1(1):181-193. doi: 10.3233/ADR-170031.
The current lack of an effective cure for dementia would exacerbate its prevalence and incidence globally. Growing evidence has linked mindfulness to cognitive and psychological improvements that could be relevant for mild cognitive impairment (MCI).
To investigate whether mindfulness practice can improve health outcomes of MCI.
The study is the first longitudinal mixed-methods observational study with a one-year follow-up period, that customized an eight-week group-based mindfulness training program for older adults with MCI ( = 14). Measures included cognitive function, psychological health, trait mindfulness, adherence to mindfulness practice, and everyday activities functioning as assessed at pre-intervention, post-intervention, and one-year follow-up. Repeated measures ANOVAs, Pearson's correlation analyses, and Mann-Whitney U tests were performed.
The MCI participants showed significant improvements in cognitive function ( < 0.05) and trait mindfulness ( < 0.05) after completing the intervention. Between program intervention and one-year follow-up (59 weeks), positive correlations were found between their cognitive function ( < 0.05) and everyday activities functioning ( < 0.05) with the duration of mindfulness meditation; and between trait mindfulness and the level of informal mindfulness practice ( < 0.05). Those who meditated more during these 59 weeks, showed greater improvements in cognitive function ( < 0.05) and everyday activities functioning ( < 0.05), with large effect sizes at the one-year follow-up. Qualitative findings will be reported separately.
Long-term mindfulness practice may be associated with cognitive and functional improvements for older adults with MCI. Mindfulness training could be a potential efficacious non-pharmacological therapeutic intervention for MCI.
目前缺乏有效的痴呆症治疗方法,这将加剧其在全球的患病率和发病率。越来越多的证据表明,正念与认知和心理改善有关,这可能与轻度认知障碍(MCI)相关。
研究正念练习是否能改善MCI的健康状况。
该研究是第一项为期一年随访期的纵向混合方法观察性研究,为患有MCI的老年人(n = 14)定制了一个为期八周的基于小组的正念训练项目。测量指标包括认知功能、心理健康、特质正念、正念练习的依从性以及干预前、干预后和一年随访时评估的日常活动功能。进行了重复测量方差分析、Pearson相关分析和Mann-Whitney U检验。
MCI参与者在完成干预后,认知功能(p < 0.05)和特质正念(p < 0.05)有显著改善。在项目干预和一年随访(59周)之间,他们的认知功能(p < 0.05)和日常活动功能(p < 0.05)与正念冥想的持续时间之间存在正相关;特质正念与非正式正念练习水平之间也存在正相关(p < 0.05)。在这59周内冥想更多的人,在认知功能(p < 0.05)和日常活动功能(p < 0.05)方面有更大的改善,在一年随访时有较大的效应量。定性研究结果将另行报告。
长期正念练习可能与MCI老年人的认知和功能改善有关。正念训练可能是一种潜在有效的MCI非药物治疗干预措施。