Innes Kim E, Selfe Terry Kit, Khalsa Dharma Singh, Kandati Sahiti
Department of Epidemiology, West Virginia University School of Public Health, Morgantown, WV, USA.
Center for the Study of Complementary and Alternative Therapies, University of Virginia Health System, Charlottesville, VA, USA.
J Alzheimers Dis. 2016 Apr 8;52(4):1277-98. doi: 10.3233/JAD-151106.
Older adults with subjective cognitive decline (SCD) are at increased risk not only for Alzheimer's disease, but for poor mental health, impaired sleep, and diminished quality of life (QOL), which in turn, contribute to further cognitive decline, highlighting the need for early intervention.
In this randomized controlled trial, we assessed the effects of two 12-week relaxation programs, Kirtan Kriya Meditation (KK) and music listening (ML), on perceived stress, sleep, mood, and health-related QOL in older adults with SCD.
Sixty community-dwelling older adults with SCD were randomized to a KK or ML program and asked to practice 12 minutes daily for 12 weeks, then at their discretion for the following 3 months. At baseline, 12 weeks, and 26 weeks, perceived stress, mood, psychological well-being, sleep quality, and health-related QOL were measured using well-validated instruments.
Fifty-three participants (88%) completed the 6-month study. Participants in both groups showed significant improvement at 12 weeks in psychological well-being and in multiple domains of mood and sleep quality (p's≤0.05). Relative to ML, those assigned to KK showed greater gains in perceived stress, mood, psychological well-being, and QOL-Mental Health (p's≤0.09). Observed gains were sustained or improved at 6 months, with both groups showing marked and significant improvement in all outcomes. Changes were unrelated to treatment expectancies.
Findings suggest that practice of a simple meditation or ML program may improve stress, mood, well-being, sleep, and QOL in adults with SCD, with benefits sustained at 6 months and gains that were particularly pronounced in the KK group.
患有主观认知衰退(SCD)的老年人不仅患阿尔茨海默病的风险增加,而且心理健康状况不佳、睡眠受损以及生活质量(QOL)下降,这些反过来又会导致进一步的认知衰退,凸显了早期干预的必要性。
在这项随机对照试验中,我们评估了为期12周的两种放松计划——克坦克里亚冥想(KK)和听音乐(ML)——对患有SCD的老年人的感知压力、睡眠、情绪和与健康相关的生活质量的影响。
60名居住在社区的患有SCD的老年人被随机分配到KK或ML计划中,并被要求每天练习12分钟,持续12周,然后在接下来的3个月里自行决定是否练习。在基线、12周和26周时,使用经过充分验证的工具测量感知压力、情绪、心理健康、睡眠质量和与健康相关的生活质量。
53名参与者(88%)完成了为期6个月的研究。两组参与者在12周时的心理健康以及情绪和睡眠质量的多个方面均有显著改善(p值≤0.05)。相对于ML组,被分配到KK组的参与者在感知压力、情绪、心理健康和生活质量-心理健康方面有更大的改善(p值≤0.09)。在6个月时,观察到的改善得以维持或进一步提高,两组在所有结果上均显示出显著且明显的改善。这些变化与治疗预期无关。
研究结果表明,简单的冥想或ML计划的练习可能会改善患有SCD的成年人的压力、情绪、幸福感、睡眠和生活质量,6个月时仍有效果,且在KK组中效果尤为明显。