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最新出炉:氯胺酮作为急诊科急性疼痛替代阿片类药物的系统评价和荟萃分析。

Hot Off the Press: A Systematic Review And Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.

机构信息

LewisGale Medical Center, Salem, VA.

Markham Stouffville Hospital, Markham, Ontario, Canada.

出版信息

Acad Emerg Med. 2019 Aug;26(8):946-948. doi: 10.1111/acem.13658. Epub 2018 Nov 27.

DOI:10.1111/acem.13658
PMID:30480346
Abstract

Ketamine has been studied as an alternative to opioids for acute pain in the emergency department setting. This review compares the effectives of intravenous ketamine at a dose of <0.5mg/kg to opioids for acute pain in adult patients. Measurements were taken within 60 minutes of administration. Ketamine was found to have similar effectiveness to opioids. Increased, but short-lived, side effects were seen with ketamine.

摘要

氯胺酮已被研究作为急诊科阿片类药物急性疼痛的替代药物。本综述比较了静脉注射剂量<0.5mg/kg 的氯胺酮与阿片类药物治疗成人急性疼痛的效果。测量是在给药后 60 分钟内进行的。研究发现,氯胺酮与阿片类药物具有相似的疗效。氯胺酮的副作用增加,但持续时间短。

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