McMaster University, Ottawa, Ontario, Canada.
Emerg Med J. 2019 Feb;36(2):128-129. doi: 10.1136/emermed-2019-208441.2.
A short cut review was carried out to establish whether low-dose ketamine is a safe and effective alternative to opioids in ED patients in acute severe pain. 76 papers were found using the reported searches, of which seven presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that low-dose ketamine can be an effective and safe alternative to opioids in acute pain management.
一篇简短的综述评估了在急诊急性剧烈疼痛的患者中，小剂量氯胺酮是否是一种安全有效的阿片类药物替代药物。使用已报告的检索方法共发现 76 篇文献，其中 7 篇文献提供了最佳证据来回答临床问题。作者、日期和国家/地区、研究的患者群体、研究类型、相关结局、这些文献的结果以及研究的局限性均被制成表格。结论是，小剂量氯胺酮可以作为急性疼痛管理中阿片类药物的有效且安全的替代药物。
