胸部 X 光检查发现的主动脉弓钙化与高血压患者肾阻力指数的关系。
Relationship between Aortic Arch Calcification, Detected by Chest X-Ray, and Renal Resistive Index in Patients with Hypertension.
机构信息
Department of Cardiology, Faculty of Medicine, Karabük University, Karabük, Turkey,
Department of Cardiology, Faculty of Medicine, Karabük University, Karabük, Turkey.
出版信息
Med Princ Pract. 2019;28(2):133-140. doi: 10.1159/000495786. Epub 2018 Nov 27.
OBJECTIVE
Aortic arch calcification (AAC) is a surrogate marker for arterial stiffness and hypertension-related vascular damage. Renal resistive index (RRI), a renal Doppler ultrasonography parameter, is used to assess renal hemodynamics. In this study, we aimed to evaluate the relationship between RRI and AAC in patients with hypertension.
METHODS
Patients with hypertension underwent a chest X-ray and re nal Doppler ultrasonography. They were divided into two groups according to RRI (group 1: RRI ≥0.70; group 2: RRI < 0.70). Two examiners, blinded to the findings of RRI, reviewed the AAC in these patients. The kappa value was detected to be 0.781 and a p value < 0.001 was considered significant.
RESULTS
The study included 289 hypertensive patients (mean age 63.87 ± 11.38 years). In 53.6% (n = 155) of the study subjects, RRI was observed to be ≥0.70. Patients with RRI ≥70 were older and had more prevalent AAC as well as left ventricular hypertrophy. A multiple linear regression analysis was carried out to test whether presence of AAC significantly predicted RRI. The results of the regression analysis indicated that presence of AAC significantly predicted RRI (β = 0.053; p < 0.001).
CONCLUSIONS
A strong and independent relationship was found between AAC on chest X-ray and RRI in patients with hypertension.
目的
主动脉弓钙化（AAC）是动脉僵硬和与高血压相关的血管损伤的替代标志物。肾阻力指数（RRI）是肾多普勒超声检查的一个参数，用于评估肾脏血流动力学。本研究旨在评估高血压患者的 RRI 与 AAC 之间的关系。
方法
高血压患者行胸部 X 线和肾脏多普勒超声检查。根据 RRI 将他们分为两组（组 1：RRI≥0.70；组 2：RRI＜0.70）。两名检查者在不知道 RRI 结果的情况下对这些患者的 AAC 进行了评估。检测到kappa 值为 0.781，p 值＜0.001 为有统计学意义。
结果
该研究共纳入 289 例高血压患者（平均年龄 63.87±11.38 岁）。在 53.6%（n=155）的研究对象中，RRI≥0.70。RRI≥70 的患者年龄较大，且更常见 AAC 和左心室肥厚。进行多元线性回归分析以检验 AAC 是否能显著预测 RRI。回归分析结果表明，AAC 的存在能显著预测 RRI（β=0.053；p＜0.001）。
结论
高血压患者胸部 X 线片上的 AAC 与 RRI 之间存在强烈的独立关系。
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