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[神经导航辅助下经皮穿刺三叉神经半月节射频热凝术治疗顽固性颅面部疼痛]

[Neuronavigation-assisted percutaneous radiofrequency thermocoagulation of trigeminal gasserian ganglion for refractory craniofacial pain].

作者信息

Zheng X B, Gao Z W, Mo H B, Lin Q, Wang H Q, Yu L H, Lin Y X, Kang D Z, Lin Z Y

机构信息

Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Neurological Center of Fujian Province, Fuzhou 350000, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2018 Nov 20;98(43):3519-3523. doi: 10.3760/cma.j.issn.0376-2491.2018.43.011.

Abstract

Percutaneous radiofrequency thermocoagulation (RFT) of the Gasserian ganglion is an effective treatment for refractory trigeminal craniofacial pain.In the present study, we assessed the feasibility of accessing the Gasserian ganglion through the foramen ovale with neuronavigation guidance in the patients of trigeminal craniofacial pain. We retrospectively analyzed forty-four patients with type Ⅰ trigeminal neuralgia who had undergone percutaneous RFT treatment in our hospital from June 2014 to December 2016.The patients were divided into fluoroscopy group and navigation group according to the intraoperative guiding manners for foramen ovale cannulation.We compared groups in terms of the duration of the whole RFT procedure and times of intraoperative fluoroscopy.We also analyzed the immediate and late outcome accessing by Barrow Neurological Institute (BNI) pain scale, as well as the complication rates in groups. There were 32 patients in the fluoroscopy group and 12 in the navigation group.The duration of the surgical procedure in navigation group was less than that in fluoroscopy group (46±12 min versus 67±16 min, =0.00), and times of intraoperative fluoroscopy was reduced (6.3±2.2 versus 1.3±1.6, =0.00). The learning curve of navigation-aid RFT was not steep in the present study overall.There was no significant difference between groups regarding pain reduction at the immediate (=0.07) or late follow-up (=0.400) time points.However, the rate of pain reduction to BNI-Ⅰ grade was greater in navigation group (=0.026). No significant difference in the complication rate between both groups, and no serious complications were observed in the both groups. Neuronavigation may be encouraged in trigeminal Gasserian ganglion RFT with better operating efficiency and less radiation exposure.The immediate and late therapeutic effects for craniofacial pain control were positive, whereas further studies are necessary.

摘要

经皮半月神经节射频热凝术(RFT)是治疗难治性三叉神经颅面痛的一种有效方法。在本研究中,我们评估了在三叉神经颅面痛患者中,在神经导航引导下经卵圆孔穿刺进入半月神经节的可行性。我们回顾性分析了2014年6月至2016年12月在我院接受经皮RFT治疗的44例Ⅰ型三叉神经痛患者。根据术中卵圆孔插管的引导方式将患者分为透视组和导航组。我们比较了两组整个RFT手术的持续时间和术中透视次数。我们还通过巴罗神经学研究所(BNI)疼痛量表分析了即刻和远期疗效,以及两组的并发症发生率。透视组有32例患者,导航组有12例患者。导航组的手术时间短于透视组(46±12分钟对67±16分钟,P=0.00),术中透视次数减少(6.3±2.2次对1.3±1.6次,P=0.00)。在本研究中,总体而言,导航辅助RFT的学习曲线并不陡峭。两组在即刻(P=0.07)或远期随访(P=0.400)时间点的疼痛减轻情况无显著差异。然而,导航组疼痛减轻至BNI-Ⅰ级的比例更高(P=0.026)。两组并发症发生率无显著差异,两组均未观察到严重并发症。在三叉神经半月神经节RFT中,神经导航可能有助于提高手术效率并减少辐射暴露。对颅面痛控制的即刻和远期治疗效果是积极的,但仍需进一步研究。

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