Canceri Josephine M, Brown Rachael, Watson Shaun R, Browne Cherylea J
School of Science and Health, Western Sydney University, Sydney, NSW, Australia.
School of Medicine, Western Sydney University, Sydney, NSW, Australia.
Front Neurol. 2018 Nov 12;9:943. doi: 10.3389/fneur.2018.00943. eCollection 2018.
Mal de Debarquement Syndrome (MdDS) is a neurological disorder which affects the vestibular system pathways, manifesting as a constant sensation of movement in the form of rocking, bobbing, or swaying. The mechanism of MdDS is poorly understood and there is a lack of awareness amongst medical professionals about the condition. This study aimed to examine treatments and symptom management strategies used by MdDS patients and evaluate their self-reported effectiveness. Motion-Triggered and Spontaneous/Other onset MdDS patients responded to a set of comprehensive questions as a retrospective survey regarding epidemiological details, diagnostic procedures, onset, and symptom triggers, hormonal influences as well as treatments and symptom management strategies used to reduce symptoms. The Motion-Triggered questionnaire was made available through Survey Monkey and the Spontaneous/Other Onset questionnaire through Qualtrics. The link for each questionnaire was made available on online MdDS support groups and on various research websites. Descriptive statistics were used for epidemiological data and Pearson's Chi Square tests were used for comparisons between and within both subtype groups. A total of 370 patients participated in the surveys, with 287 valid responses collected for the section regarding treatment and symptom management strategies. The success of the treatments and symptom management strategies did not vary between subtypes Benzodiazepines/Antidepressants were reported as being most beneficial in reducing symptoms in both groups. This was the first attempt to evaluate the reported success of treatments and symptom management strategies in MdDS patients by assessing the patients' perceived helpfulness. The treatments and symptom management strategies reported to be the most helpful in managing and/or reducing symptoms are proposed to be effective due to their stress-reducing capacities. We hope this study will broaden MdDS awareness and that this study will increase patient knowledge regarding treatments and symptom management strategies that other patients found helpful.
下船综合征(MdDS)是一种影响前庭系统通路的神经障碍,表现为持续的摇晃、摆动或 swaying 形式的运动感觉。MdDS 的机制尚不清楚,医学专业人员对该病症的认识也不足。本研究旨在检查 MdDS 患者使用的治疗方法和症状管理策略,并评估他们自我报告的有效性。运动触发型和自发/其他起病型 MdDS 患者作为回顾性调查,回答了一系列关于流行病学细节、诊断程序、起病、症状触发因素、激素影响以及用于减轻症状的治疗方法和症状管理策略的综合问题。运动触发型问卷通过 Survey Monkey 提供,自发/其他起病型问卷通过 Qualtrics 提供。每个问卷的链接在在线 MdDS 支持小组和各种研究网站上提供。描述性统计用于流行病学数据,Pearson 卡方检验用于两个亚型组之间和组内的比较。共有 370 名患者参与了调查,关于治疗和症状管理策略的部分收集到 287 份有效回复。治疗方法和症状管理策略的成功率在亚型之间没有差异。据报道,苯二氮䓬类药物/抗抑郁药在两组中减轻症状方面最有益。这是首次通过评估患者感知的帮助程度来评估 MdDS 患者中报告的治疗方法和症状管理策略的成功率。据报道,在管理和/或减轻症状方面最有帮助的治疗方法和症状管理策略因其减轻压力的能力而被认为是有效的。我们希望这项研究将拓宽对 MdDS 的认识,并且这项研究将增加患者对其他患者认为有帮助的治疗方法和症状管理策略的了解。
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