Mohammad Ali Gol Sara, Mirjalali Hamed, Asadzadeh Aghdaei Hamid, Zali Mohammad Reza
Behbood Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Parasitol. 2018 Jul-Sep;13(3):505-509.
Inflammatory bowel disease (IBD) is attributed to complex conditions of gastrointestinal tract that is frequently reported all over the world. Fecal calprotectin evaluation is described as a primary tool to screen IBD patients. There are reports showing the confounding role of some microbial agents in diagnostic levels of calprotectin. A 32-yr-old woman with symptoms like IBD/IBS (irritable bowel syndrome); admitted to IBD Clinic of Behbood Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Jan 2017 for evaluation of the level of fecal calprotectin. In spite of high level of calprotectin, trophozoite of was observed in direct examination of stool sample. Microbial pathogens can lead to false elevation of fecal calprotectin and misdiagnosis of gastrointestinal patients suspected to IBD.
炎症性肠病（IBD）是一种由复杂胃肠道状况引起的疾病，在全球范围内都有较高的发病率。粪便钙卫蛋白检测被认为是筛查IBD患者的主要手段。有报告指出，某些微生物因子在钙卫蛋白的诊断水平中起到了混淆作用。一名32岁女性，有类似IBD/肠易激综合征（IBS）的症状；于2017年1月入住伊朗德黑兰沙希德·贝赫什提医科大学贝赫布德胃肠病与肝病研究中心的IBD诊所，以评估粪便钙卫蛋白水平。尽管钙卫蛋白水平较高，但在粪便样本的直接检查中发现了 滋养体。微生物病原体可导致粪便钙卫蛋白假性升高，并对疑似IBD的胃肠疾病患者造成误诊。
