Kan Ze, Luo Wenlong, Shi Tong, Wei Chuanzhi, Han Binghao, Zheng Dejuan, Liu Shaofeng
Key Laboratory of Biobased Polymer Materials, Shandong Provincial Education Department, College of Polymer Science and Engineering, Qingdao University of Science and Technology, Qingdao, China.
Front Chem. 2018 Nov 9;6:547. doi: 10.3389/fchem.2018.00547. eCollection 2018.
Ring-opening polymerization (ROP) of cyclic esters/lactones by efficient catalysts is a powerful method for synthesis of biodegradable and biocompatible polyesters with well-defined structures. To develop catalytic systems that are fast, selective and controlled is a persistent effort of chemists. In this contribution, we report a binary urea/alkoxide catalytic system that could catalyze ROP of -LA in a fast (over 90% conversion within 1-2 min), stereoselective ( up to 0.93) and controlled manner, indicated by narrow MW distributions, linear relationship between the monomer conversions and s, end-group fidelity, and chain extension experiments. Remarkably, the catalytic system described here is simple, easily prepared, and structurally tunable and thus has versatile catalytic performances.
通过高效催化剂进行环状酯/内酯的开环聚合（ROP）是合成具有明确结构的可生物降解和生物相容性聚酯的有力方法。开发快速、选择性和可控的催化体系是化学家们一直以来的努力方向。在本论文中，我们报道了一种二元脲/醇盐催化体系，该体系能够以快速（1 - 2分钟内转化率超过90%）、立体选择性（高达0.93）和可控的方式催化ε-己内酯的ROP，这通过窄分子量分布、单体转化率与数均分子量之间的线性关系、端基保真度以及扩链实验得以证明。值得注意的是，本文所述的催化体系简单、易于制备且结构可调控，因此具有多种催化性能。
