Department of Oral and Maxillofacial Surgery, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba, 261-8502, Japan.
Department of Oral and Maxillofacial Radiology, Tokyo Dental College, 2-1-14 Misakicho, Chiyoda-ku, Tokyo, 101-0061, Japan.
Oral Radiol. 2019 Sep;35(3):272-279. doi: 10.1007/s11282-018-0357-5. Epub 2018 Oct 30.
This study investigated whether erosion and osteophyte correlates with condyle bone marrow abnormalities (BMA), as detected with quantitative T2 mapping.
Fifty-six joints (in 44 patients) that demonstrated evidence of bony erosion (ER) or osteophytes (OS) related to disc displacement without reduction were studied with MR images. A control group of 50 joints (in 50 patients) was included. The subjects were divided into five groups; noAR (control), noBMA-ER, BMA-ER, noBMA-OS, and BMA-OS. T2 mapping was performed and the regions of interest were placed over the bone marrow at the top of the condyle. The mean T2 values of the bone marrow of the mandibular condyle were calculated for all mapping images. After assessing age-related changes in T2 values of noAR group using Pearson's product-moment, differences in median T2 values of five groups were analyzed using Kruskal-Wallis test, and Steel-Dwass test (p < 0.05).
There was no significant correlation between age and T2 value in noAR group. The median T2 values of noBMA-ER and BMA-ER groups were significantly higher than those of noAR, noBMA-OS and BMA-OS groups. Those of noBMA-OS and BMA-OS groups were significantly lower than those of noAR, noBMA-ER and BMA-ER groups. There was no significant difference between noBMA and BMA groups.
It is suggested that erosion and osteophyte of the condyle may correlate with bone marrow abnormalities. T2 mapping could be show slight marrow changes of the arthritic condyle.
本研究旨在通过定量 T2 映射探讨髁突骨骨髓异常（BMA）与侵蚀和骨赘之间的关系。
对 44 例患者的 56 个关节（共 56 个关节）进行了 MRI 检查，这些关节均表现出与盘状移位无复位相关的骨侵蚀（ER）或骨赘（OS）。纳入了一个对照组（共 50 个关节）。将受试者分为五组：无 AR（对照组）、无 BMA-ER、BMA-ER、无 BMA-OS 和 BMA-OS。对 T2 图谱进行了分析，并在髁突顶部的骨髓区域放置了感兴趣区。计算了所有图谱图像中下颌骨髁突骨髓的平均 T2 值。使用 Pearson 积矩相关分析评估了无 AR 组 T2 值的年龄相关性变化，然后使用 Kruskal-Wallis 检验和 Steel-Dwass 检验（p<0.05）分析了五组之间中位数 T2 值的差异。
无 AR 组中年龄与 T2 值之间无显著相关性。无 BMA-ER 和 BMA-ER 组的中位数 T2 值明显高于无 AR、无 BMA-OS 和 BMA-OS 组。无 BMA-OS 和 BMA-OS 组的中位数 T2 值明显低于无 AR、无 BMA-ER 和 BMA-ER 组。无 BMA 组与 BMA 组之间无显著差异。
提示髁突的侵蚀和骨赘可能与骨髓异常有关。T2 图谱可以显示出关节炎性髁突的轻微骨髓变化。
