1 Department of Audiology, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Belgrade, Serbia.
2 Department of Audiology, Mater Dei Hospital, Msida, Malta.
Trends Hear. 2018 Jan-Dec;22:2331216518812251. doi: 10.1177/2331216518812251.
In children with normal cochlear acuity, middle ear fluid often abolishes otoacoustic emissions (OAEs), and negative middle ear pressure (NMEP) reduces them. No convincing evidence of beneficial pressure compensation on distortion product OAE (DPOAE) has yet been presented. Two studies aimed to document effects of NMEP on transient OAE (TEOAE) and DPOAE. In Study 1, TEOAE and DPOAE pass/fail responses were analyzed before and after pressure compensation in 50 consecutive qualifying referrals having NMEP from -100 to -299 daPa. Study 2 concentrated on DPOAE, recording both amplitude (distortion product amplitude) and signal-to-noise ratio (SNR) before and after pressure compensation. Of the 20 participants, 5 had both ears qualifying. An effect of compensation on meeting a pass criterion was present in TEOAE for both left and right ear data in Study 1 but not demonstrable in DPOAE. In Study 2, the distortion product amplitude compensation effect was marginal overall, and depended on recording frequency band. SNR values improved moderately after pressure compensation in the two (overlapping) sets of single-ear data. In the five cases with both ears qualifying, a stronger compensation effect size, over 3 dB, was seen. The absolute dependence of SNR on frequency was also strongly replicated, but in no analysis, the frequency × compensation interaction was significant. Independent of particular frequency range, the data support a limited SNR improvement in 2 to 3 dB for compensation in DPOAE, with slightly larger effects in ears giving SNRs between 0 dB and +6 dB, where pass/fail cutoffs would generally be located.
在听力正常的儿童中，中耳液通常会使耳声发射（OAE）消失，而负中耳压力（NMEP）则会降低它们。目前还没有令人信服的证据表明，对畸变产物耳声发射（DPOAE）的压力补偿有益。有两项研究旨在记录 NMEP 对瞬态耳声发射（TEOAE）和 DPOAE 的影响。在研究 1 中，对 50 例连续的有 NMEP（范围为-100 至-299daPa）的合格转诊患者，在压力补偿前后分析 TEOAE 和 DPOAE 的通过/失败反应。研究 2 集中于 DPOAE，在压力补偿前后记录幅度（畸变产物幅度）和信噪比（SNR）。在 20 名参与者中，有 5 名双耳均符合条件。在研究 1 中，左耳和右耳数据的 TEOAE 均表现出补偿对通过标准的影响，但在 DPOAE 中则无法证明。在研究 2 中，整体而言，畸变产物幅度补偿效果是边缘性的，并且取决于记录的频带。在两个（重叠）单耳数据集中，压力补偿后 SNR 值适度提高。在符合双耳合格条件的五例中，观察到更强的补偿效果大小，超过 3dB。SNR 值对频率的绝对依赖性也得到了强烈的复制，但在没有分析中，频率×补偿的相互作用并不显著。独立于特定的频率范围，数据支持 DPOAE 补偿时 SNR 提高 2 至 3dB，在 SNR 介于 0dB 和+6dB 的耳朵中，效果略大，而这些通常是通过/失败的截止值。
