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对巴西南部一个城市十年间进行的斑贴试验结果的评估。

Assessment of patch test results carried out during ten years in a city in southern Brazil.

作者信息

Corrêa-Fissmer Mariane, Dalazen Cintia Camila, Ferreira Bárbara Piacentini, Iser Betine Pinto Moehlecke

机构信息

Outpatient Clinic of Medical Specialties, Universidade do Sul de Santa Catarina, Tubarão (SC), Brazil.

Medical Outpatient Clinic, Clínica Heidelberg, Curitiba (PR), Brazil.

出版信息

An Bras Dermatol. 2018 Nov/Dec;93(6):807-812. doi: 10.1590/abd1806-4841.20185023.

DOI:10.1590/abd1806-4841.20185023
PMID:30484523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6256204/
Abstract

BACKGROUND

Contact dermatitis affects up to 20% of the population. Patch testing for contact allergy may be needed to confirm the diagnosis.

OBJECTIVES

To describe and discuss the results of patch tests performed in a city in southern Brazil.

METHODS

A cross-sectional analysis was performed on all skin test results over ten years. Variables such as gender, age at the time of testing, and test results were evaluated. Triggering factors, duration of complain, and previous medications used related to the clinical history were retrieved for some patients by reviewing their medical records.

RESULTS

The sample was composed of 539 patch tests, of which 411 (76.2%) were from women. The age of the tested subjects ranged from 5 to 87 years. The prevalence of positive reactions in the patch tests was 391 (72.5%). The most prevalent positive reaction was to nickel sulfate (196; 36.4%), which had statistical significance when associated with female gender (p<0,001).

STUDY LIMITATIONS

Database obtained through secondary sources (the reports of the exams and the medical records), occurring the incomplete registration of some information.

CONCLUSIONS

Data analysis at the local level is important to define preventive policies.

摘要

背景

接触性皮炎影响着高达20%的人口。可能需要进行斑贴试验以确认接触性过敏的诊断。

目的

描述并讨论在巴西南部一个城市进行的斑贴试验结果。

方法

对十年内所有皮肤试验结果进行横断面分析。评估了性别、测试时的年龄以及测试结果等变量。通过查阅部分患者的病历,获取了与临床病史相关的诱发因素、症状持续时间以及之前使用的药物。

结果

样本包括539次斑贴试验,其中411次(76.2%)来自女性。受试对象的年龄在5至87岁之间。斑贴试验中阳性反应的患病率为391次(72.5%)。最常见的阳性反应是对硫酸镍(196次;36.4%),与女性相关时具有统计学意义(p<0.001)。

研究局限性

通过二手资料(检查报告和病历)获得数据库,部分信息登记不完整。

结论

地方层面的数据分析对于制定预防政策很重要。

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Actas Dermosifiliogr. 2017 Jul-Aug;108(6):571-578. doi: 10.1016/j.ad.2016.12.018. Epub 2017 Mar 8.
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Allergic contact dermatitis: Patient management and education.变应性接触性皮炎:患者管理与教育。
J Am Acad Dermatol. 2016 Jun;74(6):1043-54. doi: 10.1016/j.jaad.2015.02.1144.
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Elicitation threshold of cobalt chloride: analysis of patch test dose-response studies.钴氯化物的激发阈值:斑贴试验剂量反应研究分析。
Contact Dermatitis. 2016 Feb;74(2):105-9. doi: 10.1111/cod.12499. Epub 2015 Nov 13.
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Risk factors for common contact allergens and patch test results using a modified European baseline series in patients tested during between 2000 and 2009 at Siriraj Hospital.在 2000 年至 2009 年间于 Siriraj 医院接受检测的患者中,使用改良的欧洲基本系列进行斑贴试验,以确定常见接触过敏原的危险因素和斑贴试验结果。
Asian Pac J Allergy Immunol. 2014 Mar;32(1):60-5. doi: 10.12932/AP0326.32.1.2014.
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Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period.巴西接触性皮炎研究小组在2006年至2011年期间推荐的斑贴试验标准系列。
An Bras Dermatol. 2013 Nov-Dec;88(6):1015-8. doi: 10.1590/abd1806-4841.20132374.
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