Serrão Lucas Mariano, Sarmenghi Karina Demoner de Abreu, Pinto Barbara Christina Bonino Pereira, Miranda Paulo Bittencourt de
Dermatology Service, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brazil.
Department of Dermatopathology, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brasil.
An Bras Dermatol. 2018 Nov/Dec;93(6):881-883. doi: 10.1590/abd1806-4841.20187462.
Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin. Circumcision is the most effective treatment; however, it can be hard for patients to accept. As an alternative, topical calcineurin inhibitors are used, with good response. This article reports the case of a 32-year-old patient, HIV carrier, diagnosed with Zoon's plasma cell balanitis. Treatment with topical tacrolimus was administered, without improvement. A 6-week course of thalidomide resulted in complete remission of the lesions, without recurrence after eight months of follow-up.
浆细胞性龟头炎是一种慢性生殖器炎性皮肤病，影响未行包皮环切术的男性，尤其是老年人。其特征为位于阴茎头和包皮上的无痛性橙色红斑。包皮环切术是最有效的治疗方法；然而，患者可能难以接受。作为替代方法，可使用外用钙调神经磷酸酶抑制剂，效果良好。本文报告了一例32岁的HIV携带者患者，诊断为浆细胞性龟头炎。外用他克莫司治疗无效。沙利度胺治疗6周后皮损完全缓解，随访8个月无复发。
