蛋白质芳香族氨基酸在伴刀豆球蛋白A-碳水化合物相互作用中的作用。一项辐射分解研究。
Implication of protein aromatic amino acids in concanavalin A-carbohydrate interactions. A radiolytic study.
作者信息
Davies J V, Moore J S, Mudher S
出版信息
Int J Radiat Biol Relat Stud Phys Chem Med. 1978 Jan;33(1):11-9. doi: 10.1080/09553007714551451.
Pulse radiolysis and 60Co gamma-radiolysis have been used to study the effects of ionizing radiation on the glycogen-precipitating activity of the protein concanavalin A. Both eaq- and OH. react extremely rapidly with the protein and contribute to the observed loss of concanavalin A activity. Evidence is also presented that (Br)2-. and (SCN)2-. react with with tyrosine and tryptophan residues in concanavalin A, which is also accompanied by loss of glycogen precipitation activity.
脉冲辐解和钴60γ辐解已被用于研究电离辐射对伴刀豆球蛋白A糖原沉淀活性的影响。水合电子（eaq-）和羟基自由基（OH.）都能与该蛋白质迅速反应，并导致观察到的伴刀豆球蛋白A活性丧失。同时也有证据表明，二溴负离子（(Br)2-）和二硫氰根负离子（(SCN)2-）能与伴刀豆球蛋白A中的酪氨酸和色氨酸残基发生反应，这也伴随着糖原沉淀活性的丧失。
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