Gaszynski Rafael, Lim Christopher, Chan Daniel L, Fisher Oliver M, Das Kamala Kanta, Merrett Neil, Wilson Robert, Cosman Peter
Upper Gastrointestinal Surgery Unit, Liverpool Hospital, Sydney, New South Wales, Australia.
Department of Surgery, Campbelltown Hospital, Sydney, New South Wales, Australia.
ANZ J Surg. 2019 May;89(5):492-496. doi: 10.1111/ans.14928. Epub 2018 Nov 28.
Symptomatic cholelithiasis accounts for a significant burden of emergency general surgical presentations in Australia and the Western population. Access to hepatobiliary ultrasonography to facilitate diagnosis can lead to delays in timely treatment. Surgical ultrasonography at the bedside (SUB) can mitigate this barrier to patient care. This study assessed the diagnostic accuracy of SUB by trainees versus formal ultrasonographer or computed tomography examination for suspected symptomatic cholelithiasis.
A prospective non-inferiority study of emergency patient admissions with abdominal pain in two tertiary referral hospitals during July 2017 to October 2018 was performed. Results of SUB were compared with accredited radiographer ultrasonography or computed tomography and histopathological assessment. Positive findings at SUB for symptomatic cholelithiasis included: cholelithiasis, gallbladder wall thickness ˃3 mm, pericholecystic fluid or sonographic Murphy's sign.
One hundred patients with epigastric or right upper quadrant pain underwent SUB. Mean patient age was 49 years (range 20-90 years), with 61 females and 39 males. Sensitivity and specificity for diagnosis of symptomatic cholelithiasis was 94.9% and 100% for SUB and 98.7% and 100% for accredited radiographers. Diagnostic accuracy was 96% for SUB and 99% for radiographer ultrasonography. Positive predictive value and negative predictive value were 100% and 84.6% for SUB and 100% and 96% for radiographers. The inter-rater reliability for features compatible with the diagnosis of symptomatic cholelithiasis was good with a kappa of 0.758 (95% confidence interval 0.587-0.929, P < 0.001).
This first Australian experience demonstrates that general surgical trainees can accurately diagnose cholecystitis with SUB and this assessment is not inferior and has substantial agreement with accredited radiographer ultrasonography.
在澳大利亚和西方人群中,有症状的胆结石是急诊普通外科就诊的一个重要负担。进行肝胆超声检查以辅助诊断可能会导致治疗延迟。床旁手术超声检查(SUB)可以消除这一患者护理障碍。本研究评估了实习医生进行的SUB与专业超声检查人员或计算机断层扫描检查对疑似有症状胆结石的诊断准确性。
对2017年7月至2018年10月期间两家三级转诊医院因腹痛急诊入院的患者进行了一项前瞻性非劣效性研究。将SUB的结果与经认可的放射技师超声检查或计算机断层扫描以及组织病理学评估结果进行比较。SUB诊断有症状胆结石的阳性发现包括:胆结石、胆囊壁厚度>3mm、胆囊周围积液或超声墨菲氏征。
100例上腹部或右上腹疼痛的患者接受了SUB检查。患者平均年龄为49岁(范围20 - 90岁),其中女性61例,男性39例。SUB诊断有症状胆结石的敏感性和特异性分别为94.9%和100%,经认可的放射技师分别为98.7%和100%。SUB的诊断准确性为96%,放射技师超声检查为99%。SUB的阳性预测值和阴性预测值分别为100%和84.6%,放射技师分别为100%和96%。与有症状胆结石诊断相符的特征的评分者间信度良好,kappa值为0.758(95%置信区间0.587 - 0.929,P<0.001)。
澳大利亚的这首次经验表明,普通外科实习医生可以通过SUB准确诊断胆囊炎,且这种评估并不逊色于经认可的放射技师超声检查,两者有高度一致性。