Grigg M J, Nicolaides A N, Wolfe J H
Irvine Laboratory for Cardiovascular Investigation and Research, St. Mary's Hospital Medical School, London, UK.
Br J Surg. 1988 Aug;75(8):737-40. doi: 10.1002/bjs.1800750806.
Eighty femorodistal in situ vein bypass grafts have been evaluated at 3-monthly intervals clinically, with ankle:brachial pressure indices (ABI), by intravenous digital subtraction angiography (IV DSA) and by Duplex scanning. Five grafts (6 per cent) failed in the perioperative period. Nineteen (25 per cent) of the remaining 75 grafts subsequently developed stenoses on IV DSA during the first 12 months. All angiographic stenoses were detected by Duplex scanning using velocity ratio criteria before the development of symptoms or a measurable decline in ABI, i.e. while non-haemodynamically significant. This technique involves scanning the entire length of the graft but allows even minor stenoses to be detected and progression of stenoses can be determined. At a mean follow-up of 12 months (3-18 months), four (7 per cent) of the fifty-six grafts without stenoses occluded. Eight (42 per cent) of the nineteen stenosed grafts either occluded or developed symptoms. None of the occluded grafts in this series could be salvaged. Non-haemodynamically significant vein stenoses can be detected non-invasively, occur frequently and are associated with graft failure.
对80条原位股腘静脉搭桥移植血管每3个月进行一次临床评估,测量踝肱压力指数(ABI),采用静脉数字减影血管造影(IV DSA)和双功超声扫描。5条移植血管(6%)在围手术期失败。其余75条移植血管中有19条(25%)在最初12个月内IV DSA检查发现出现狭窄。所有血管造影显示的狭窄在症状出现或ABI出现可测量下降之前,即血流动力学无明显异常时,通过双功超声扫描利用速度比标准检测到。该技术需要扫描移植血管的全长,但能够检测到即使是轻微的狭窄,并可确定狭窄的进展情况。平均随访12个月(3 - 18个月),56条无狭窄的移植血管中有4条(7%)闭塞。19条狭窄的移植血管中有8条(42%)发生闭塞或出现症状。该系列中所有闭塞的移植血管均无法挽救。血流动力学无明显异常的静脉狭窄可通过非侵入性方法检测到,经常出现且与移植血管失败相关。