Wolfe J H, Thomas M L, Jamieson C W, Browse N L, Burnand K G, Rutt D L
Br J Surg. 1987 Apr;74(4):268-70. doi: 10.1002/bjs.1800740414.
Detection and early correction of stenoses following femorodistal bypass grafting may prevent graft occlusion. We studied 43 grafts (36 saphenous vein and 7 human umbilical vein) prospectively by peroperative angiography and then by clinical assessment, post-exercise Doppler ankle pressures and digital subtraction angiography at 1 week, 3 months, 6 months and 1 year. There were 11 grafts inserted for critical ischaemia, 16 for rest pain and 16 for disabling claudication. Four patients died within the year with five patient grafts and these were excluded from the final results. Eight grafts failed during the first year; four within 1 month and a further four subsequently, with no warning alteration of symptoms, ankle Doppler pressure or digital subtraction angiography. Four additional grafts were jeopardized by symptomatic stenoses. Six grafts developed an asymptomatic stenosis of greater than 50 per cent without a change in exercising ankle Doppler pressure. Three symptomatic stenoses were successfully revised but the fourth occluded on conservative management. Three asymptomatic stenoses have also been successfully revised and three have been treated conservatively. Close surveillance of femorodistal grafts is justified by this study but a deterioration in ankle brachial Doppler index was only useful in the patients with recurrent symptoms and was unable to detect half the stenoses of greater than 50 per cent. The detection of these by intravenous digital subtraction angiography might help to avoid graft failure.
股腘动脉搭桥术后狭窄的检测及早期纠正可预防移植血管闭塞。我们对43条移植血管(36条大隐静脉和7条人脐静脉)进行了前瞻性研究,术中通过血管造影,随后在术后1周、3个月、6个月和1年通过临床评估、运动后多普勒踝压及数字减影血管造影进行观察。其中11条移植血管用于治疗严重缺血,16条用于缓解静息痛,16条用于治疗致残性间歇性跛行。年内有4例患者死亡,其5条移植血管被排除在最终结果之外。第一年有8条移植血管失败;4条在1个月内失败,另外4条随后失败,症状、踝部多普勒压力或数字减影血管造影均无预警性改变。另有4条移植血管因有症状的狭窄而受到威胁。6条移植血管出现无症状性狭窄,狭窄程度大于50%,运动时踝部多普勒压力无变化。3条有症状的狭窄成功进行了修复,但第4条在保守治疗时闭塞。3条无症状性狭窄也成功进行了修复,3条采用保守治疗。本研究证明对股腘动脉移植血管进行密切监测是合理的,但踝臂多普勒指数的恶化仅对有复发症状的患者有用,且无法检测出一半以上狭窄程度大于50%的狭窄。通过静脉数字减影血管造影检测这些狭窄可能有助于避免移植血管失败。