Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California.
Department of Anesthesia, UCLA David Geffen School of Medicine, Los Angeles, California.
Semin Respir Crit Care Med. 2018 Oct;39(5):609-624. doi: 10.1055/s-0038-1675333. Epub 2018 Nov 28.
Liver transplantation (LT) has the potential to cure patients with acute and chronic liver failure as well as a number of hepatic and biliary malignancies. Over time, due to the increasing demand for organs as well as improvements in the survival of LT recipients, patients awaiting LT have become sicker, and often undergo the procedure while critically ill. This trend has made the process of preoperative assessment and planning, intraoperative management, and postoperative management even more crucial to the success of LT programs. Multidisciplinary and specialized teams are essential and include anesthesiologists, surgeons, and intensivists. This article focuses on the preoperative evaluation, intraoperative care, and postoperative management of the liver transplant patient. Management relevant to the critically ill patient is discussed, with a focus on the management of postoperative cardiopulmonary conditions including the care of special populations such as those with hepatopulmonary syndrome and portopulmonary hypertension.
肝移植(LT)有潜力治愈急性和慢性肝功能衰竭以及多种肝和胆道恶性肿瘤的患者。随着时间的推移,由于对器官的需求不断增加以及 LT 受者的生存率提高,等待 LT 的患者病情变得更加严重,并且经常在病危的情况下进行该手术。这一趋势使得 LT 计划的术前评估和规划、术中管理以及术后管理变得更加关键。多学科和专业团队至关重要,包括麻醉师、外科医生和重症监护医生。本文重点介绍肝移植患者的术前评估、术中护理和术后管理。讨论了与重症患者管理相关的内容,重点是术后心肺状况的管理,包括对特殊人群(如患有肝肺综合征和门脉高压肺的人群)的护理。