• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Botulinum Neurotoxins (BoNTs)-Antibody and Vaccine.肉毒神经毒素（BoNTs）-抗体和疫苗。
Toxins (Basel). 2018 Nov 26;10(12):495. doi: 10.3390/toxins10120495.
2
Vaccination of cattle with a recombinant bivalent toxoid against botulism serotypes C and D.牛用 C 型和 D 型肉毒梭菌双价类毒素重组疫苗进行免疫接种。
Vaccine. 2014 Jan 3;32(2):214-6. doi: 10.1016/j.vaccine.2013.11.025. Epub 2013 Nov 16.
3
Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D.水牛对 C 型和 D 型肉毒梭菌重组疫苗的体液免疫反应。
Toxins (Basel). 2017 Sep 22;9(10):297. doi: 10.3390/toxins9100297.
4
Protective efficacy of recombinant bacterin vaccine against botulism in cattle.重组菌苗疫苗对牛肉毒梭菌病的保护效力。
Vaccine. 2020 Mar 4;38(11):2519-2526. doi: 10.1016/j.vaccine.2020.01.089. Epub 2020 Feb 6.
5
Potent tetravalent replicon vaccines against botulinum neurotoxins using DNA-based Semliki Forest virus replicon vectors.基于 DNA 的 Semliki Forest 病毒复制子载体的高效四价复制子疫苗抗肉毒神经毒素。
Vaccine. 2013 May 7;31(20):2427-32. doi: 10.1016/j.vaccine.2013.03.046. Epub 2013 Apr 10.
6
Immunogenicity of a Bivalent Non-Purified Recombinant Vaccine against Botulism in Cattle.牛用双价非精制重组肉毒梭菌疫苗的免疫原性。
Toxins (Basel). 2018 Sep 20;10(10):381. doi: 10.3390/toxins10100381.
7
Antibodies and Vaccines against Botulinum Toxins: Available Measures and Novel Approaches.抗肉毒杆菌毒素的抗体与疫苗：现有措施及新方法
Toxins (Basel). 2019 Sep 12;11(9):528. doi: 10.3390/toxins11090528.
8
Pentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors.使用基于DNA的Semliki森林病毒复制子载体的抗肉毒杆菌神经毒素和破伤风毒素的五价复制子疫苗。
Hum Vaccin Immunother. 2014;10(7):1874-9. doi: 10.4161/hv.28937.
9
Dual-route targeted vaccine protects efficiently against botulinum neurotoxin A complex.双路靶向疫苗能有效预防肉毒梭菌神经毒素 A 复合物。
Vaccine. 2018 Jan 2;36(1):155-164. doi: 10.1016/j.vaccine.2017.11.008. Epub 2017 Nov 24.
10
Development and evaluation of candidate subunit vaccine and novel antitoxin against botulinum neurotoxin serotype E.E 型肉毒神经毒素候选亚单位疫苗和新型抗毒素的研发与评价。
Hum Vaccin Immunother. 2020;16(1):100-108. doi: 10.1080/21645515.2019.1633878. Epub 2019 Jul 26.

引用本文的文献

1
Novel platform for engineering stable and effective vaccines against botulinum neurotoxins A, B and E.新型平台可用于研发针对肉毒神经毒素 A、B 和 E 的稳定且有效的疫苗。
Front Immunol. 2024 Sep 9;15:1469919. doi: 10.3389/fimmu.2024.1469919. eCollection 2024.
2
Biological and Immunological Characterization of a Functional L-HN Derivative of Botulinum Neurotoxin Serotype F.功能性 L-HN 衍生型 F 型肉毒神经毒素的生物学和免疫学特性。
Toxins (Basel). 2023 Mar 6;15(3):200. doi: 10.3390/toxins15030200.
3
Development and evaluation of a tetravalent botulinum vaccine.开发和评估一种四价肉毒杆菌疫苗。
Hum Vaccin Immunother. 2022 Nov 30;18(5):2048621. doi: 10.1080/21645515.2022.2048621. Epub 2022 Apr 18.
4
Functional EL-HN Fragment as a Potent Candidate Vaccine for the Prevention of Botulinum Neurotoxin Serotype E.功能性 EL-HN 片段作为预防肉毒梭菌神经毒素血清型 E 的有效候选疫苗。
Toxins (Basel). 2022 Feb 11;14(2):135. doi: 10.3390/toxins14020135.

本文引用的文献

1
A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.一种三抗体混合物能有效中和多种肉毒梭菌神经毒素 E 型亚型。
Toxins (Basel). 2018 Mar 1;10(3):105. doi: 10.3390/toxins10030105.
2
A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.一种三表位单价抗体在中和 A 型肉毒神经毒素方面几乎重现了三种单克隆抗体组合的效力。
Toxins (Basel). 2018 Feb 15;10(2):84. doi: 10.3390/toxins10020084.
3
The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies.欧洲 AntibotABE 框架计划及其更新：创新性肉毒杆菌抗体的开发。
Toxins (Basel). 2017 Oct 2;9(10):309. doi: 10.3390/toxins9100309.
4
Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D.水牛对 C 型和 D 型肉毒梭菌重组疫苗的体液免疫反应。
Toxins (Basel). 2017 Sep 22;9(10):297. doi: 10.3390/toxins9100297.
5
Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism.重组肉毒神经毒素 Hc 亚单位（BoNT Hc）和无活性的梭状芽胞杆菌全毒素（ciBoNT HPs）作为预防肉毒中毒的疫苗候选物。
Toxins (Basel). 2017 Sep 3;9(9):269. doi: 10.3390/toxins9090269.
6
Vaccines against Botulism.肉毒杆菌疫苗。
Toxins (Basel). 2017 Sep 2;9(9):268. doi: 10.3390/toxins9090268.
7
Efficacy and Safety of Letibotulinum Toxin A for the Treatment of Dynamic Equinus Foot Deformity in Children with Cerebral Palsy: A Randomized Controlled Trial.肉毒毒素 A 治疗脑瘫儿童动态马蹄内翻足畸形的疗效和安全性：一项随机对照试验。
Toxins (Basel). 2017 Aug 18;9(8):252. doi: 10.3390/toxins9080252.
8
SiMa Cells for a Serotype Specific and Sensitive Cell-Based Neutralization Test for Botulinum Toxin A and E.用于A型和E型肉毒杆菌毒素血清型特异性和灵敏的基于细胞的中和试验的SiMa细胞。
Toxins (Basel). 2017 Jul 20;9(7):230. doi: 10.3390/toxins9070230.
9
Role of Homologous Fc Fragment in the Potency and Efficacy of Anti-Botulinum Antibody Preparations.同源Fc片段在抗肉毒杆菌抗体制剂效力和疗效中的作用
Toxins (Basel). 2017 May 29;9(6):180. doi: 10.3390/toxins9060180.
10
RBC Adherence of Immune Complexes Containing Botulinum Toxin Improves Neutralization and Macrophage Uptake.含有肉毒杆菌毒素的免疫复合物与红细胞的黏附可增强中和作用及巨噬细胞摄取。
Toxins (Basel). 2017 May 19;9(5):173. doi: 10.3390/toxins9050173.

肉毒神经毒素（BoNTs）-抗体和疫苗。

Botulinum Neurotoxins (BoNTs)-Antibody and Vaccine.

机构信息

Department of Anesthesia and Perioperative Care, University of California, San Francisco, Zuckerberg San Francisco General Hospital and Trauma Center, Room 3C-38, 1001 Potrero Avenue, San Francisco, CA 94110, USA.

出版信息

Toxins (Basel). 2018 Nov 26;10(12):495. doi: 10.3390/toxins10120495.

DOI:10.3390/toxins10120495
PMID:30486254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6315911/
Abstract

Botulism, caused by exposure to one or more of the eight serotypes of botulinum neurotoxins (BoNTs) (BoNT/A through H), is often fatal without rapid treatment. [...].

摘要

肉毒中毒是由接触一种或多种（BoNT/A 至 H）8 种血清型肉毒神经毒素引起的，如果不迅速治疗，通常是致命的。[... ]。