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植物化学成分分析、抗氧化和抗糖尿病活性的研究——来自马里的猴面包树(Baobab),作为促进健康化合物的来源。

Phytochemical Profile, Antioxidant and Antidiabetic Activities of Adansonia digitata L. (Baobab) from Mali, as a Source of Health-Promoting Compounds.

机构信息

Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.

Research Centre for Nutraceutical and Healthy Foods "NUTRAFOOD", University of Pisa, 56124 Pisa, Italy.

出版信息

Molecules. 2018 Nov 27;23(12):3104. doi: 10.3390/molecules23123104.

DOI:10.3390/molecules23123104
PMID:30486448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6321735/
Abstract

UNLABELLED

: L. (Malvaceae), also known as baobab, is a tree attracting recent interest especially due to the high nutritional value of the fruit pulp. However, few studies are reported on the secondary metabolite content, showing high variability depending on the geographic region.

METHODS

In this study, the chemical profiles of Malian commercial baobab fruits and leaves, focused on phenolic content, were investigated by HPLC coupled with a photodiode array (PDA)/UV and an electrospray ionization (ESI) mass spectrometer (MS) and gas chromatography (GC)/MS. In addition, the extracts of fruit pulps obtained from three different markets (Fruits 1, 2, and 3) were evaluated for their total phenolic content (TPC), antioxidant activity and α-glucosidase inhibition.

RESULTS

Baobab fruit pulps were found to be rich in procyanidins and flavonol glycosides, with tiliroside as the major constituent. The baobab leaves showed a similar profile respect to the fruits, but with more detected phenolics. All fruit pulp extracts exerted antioxidant activity (highest for Fruit 3) and higher α-glucosidase inhibition than acarbose used as standard.

CONCLUSIONS

This study confirmed the variability of baobab with different origins and indicated Malian species baobab as a promising source of health-promoting substances.

摘要

未加标签

猴面包树(Malvaceae),也被称为猴面包树,是一种近年来引起人们关注的树,特别是因为其果肉的高营养价值。然而,关于其次生代谢物含量的研究很少,表明其取决于地理位置而具有高度的可变性。

方法

在这项研究中,通过高效液相色谱法(HPLC)与光电二极管阵列(PDA)/紫外(UV)和电喷雾电离(ESI)质谱(MS)以及气相色谱(GC)/ MS 联用,对马里商业猴面包树果实和叶子的化学成分进行了研究,重点是酚类含量。此外,还评估了从三个不同市场(水果 1、2 和 3)获得的果实浆提取物的总酚含量(TPC)、抗氧化活性和α-葡萄糖苷酶抑制活性。

结果

发现猴面包树果实浆富含原花青素和类黄酮糖苷,以三叶豆苷为主要成分。猴面包树叶子的图谱与果实相似,但检测到的酚类物质更多。所有的果实浆提取物都具有抗氧化活性(水果 3 的活性最高),并且比作为标准的阿卡波糖具有更高的α-葡萄糖苷酶抑制活性。

结论

这项研究证实了不同来源的猴面包树的可变性,并表明马里猴面包树是一种有前途的具有促进健康作用的物质来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/96043f95fa9d/molecules-23-03104-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/f061e57a616f/molecules-23-03104-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/f937adad4c0e/molecules-23-03104-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/0fbbe8ab443b/molecules-23-03104-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/96043f95fa9d/molecules-23-03104-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/f061e57a616f/molecules-23-03104-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/f937adad4c0e/molecules-23-03104-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/0fbbe8ab443b/molecules-23-03104-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6c/6321735/96043f95fa9d/molecules-23-03104-g004a.jpg

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