Centro de Investigação Interdisciplinar Egas Moniz, Instituto Universitário Egas Moniz, Campus Universitário, Quinta da Granja, Monte de Caparica, 2829-511 Caparica, Portugal.
Nutrients. 2023 May 1;15(9):2170. doi: 10.3390/nu15092170.
L. fruit, also known as baobab, has been used traditionally throughout the world for its medicinal properties. Ethnopharmacological uses of various plant parts have been reported for hydration, antipyretic, antiparasitic, antitussive, and sudorific properties and also in the treatment of diarrhea and dysentery in many African countries. Several studies have revealed that in addition to these applications, baobab has antioxidant, anti-inflammatory, analgesic, and antimicrobial activities. The health benefits of baobab have been attributed to its bioactive compounds, namely phenols, flavonoids, proanthocyanins, tannins, catechins, and carotenoids. Baobab fruit is also an important source of vitamin C and micronutrients, including zinc, potassium, magnesium, iron, calcium, and protein, which may reduce nutritional deficiencies. Despite scientific studies revealing that this fruit has a wide diversity of bioactive compounds with beneficial effects on health, there is a gap in the review of information about their mechanisms of action and critical analysis of clinical trials exploring, in particular, their effect on glycemia regulation. This work aims to present a current overview of the bioactive compounds, biological activities, and effects of fruit on blood glucose, highlighting their potential mechanisms of action and effects on glycemia regulation, evaluated in recent animal and human trials.
乐果，也被称为猴面包树，因其药用特性而在世界各地被传统使用。各种植物部位的民族药理学用途已被报道用于水合作用、退热、驱虫、镇咳和发汗作用，以及在许多非洲国家治疗腹泻和痢疾。几项研究表明，除了这些应用之外，猴面包树还具有抗氧化、抗炎、镇痛和抗菌活性。猴面包果的健康益处归因于其生物活性化合物，即酚类、类黄酮、原花青素、单宁、儿茶素和类胡萝卜素。猴面包果也是维生素 C 和微量营养素的重要来源，包括锌、钾、镁、铁、钙和蛋白质，这可能会减少营养缺乏。尽管科学研究表明，这种水果具有广泛的生物活性化合物，对健康有有益的影响，但在审查关于其作用机制的信息以及对临床试验的批判性分析方面存在差距，特别是它们对血糖调节的影响。这项工作旨在介绍水果的生物活性化合物、生物活性以及对血糖的影响的最新概述，强调其在血糖调节中的潜在作用机制和影响，这些作用机制和影响是在最近的动物和人体试验中评估的。
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