Lu Hongyan, Guo Zaiyu, Liu Jie, Zhang Heliang, Zhao Wei, Wu Yanan, Ni Jingxian, Liu Wei, Tu Jun, Wang Jinghua, Ning Xianjia, Zhang Jianning
Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, 300052, China.
Aging (Albany NY). 2018 Nov 28;10(11):3438-3449. doi: 10.18632/aging.101657.
In China, >70% of stroke deaths occur in people aged ≥65 years. However, trends in the stroke incidence among elderly people are unclear. We aimed to determine trends in the stroke incidence among elderly people in rural China. This was a population-based surveillance study conducted in Tianjin, China. Stroke events and all deaths were registered annually. Trends and annual proportion of change in incidence of first-ever stroke were evaluated from 1992 to 2016. The age-standardized incidence of first-ever stroke increased annually by 3.7% overall in elderly people (2.7% for men; 5.0% for women; all P<0.05). However, from 2008 to 2016, there was no significant change in the trends of stroke incidence among elderly people, across gender and subtypes. The proportion of elderly patients with first-ever stroke decreased by 1.1% annually. In contrast to young patients, annual changes in the incidence of stroke tended to be slight in elderly patients (3.7% vs. 9.5%) with greater increase in female patients than those in male patients (2.7% vs. 10.3% for men; 5.0% vs. 8.9% for women). Thus, the control of risk factors for stroke among elderly people is crucial, especially among older women, to reduce the burden of stroke in China.
在中国，超过70%的中风死亡发生在65岁及以上人群中。然而，老年人中风发病率的趋势尚不清楚。我们旨在确定中国农村老年人中风发病率的趋势。这是一项在中国天津开展的基于人群的监测研究。每年登记中风事件和所有死亡情况。评估了1992年至2016年首次中风发病率的趋势和年度变化比例。总体而言，老年人首次中风的年龄标准化发病率每年上升3.7%（男性为2.7%；女性为5.0%；所有P<0.05）。然而，从2008年到2016年，无论性别和亚型，老年人中风发病率趋势均无显著变化。首次中风的老年患者比例每年下降1.1%。与年轻患者相比，老年患者中风发病率的年度变化往往较小（3.7%对9.5%），女性患者的增幅大于男性患者（男性为2.7%对10.3%；女性为5.0%对8.9%）。因此，控制老年人中风的危险因素对于减轻中国的中风负担至关重要，尤其是老年女性。
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