Liu Jie, Yang Qiaoxia, Zhang Xin, Lin Qiuxing, Yang Yuan, Guo Dandan, Mao Wenjing, Tu Jun, Liu Zeping, Li Jidong, Ning Xianjia, Wang Jinghua
Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China.
Front Neurol. 2021 Jan 25;11:596871. doi: 10.3389/fneur.2020.596871. eCollection 2020.
This study aimed to explore trends in the burden from stroke associated with home quarantine during the COVID-19 pandemic. Patients with a first-ever stroke registered between January 1 and April 20 from 2010 to 2020 were included in this study. We compared the incidence and the rates of mortality, hospitalization, and diagnosis by neuroimaging for first-ever stroke among a low-income population in rural China during the study periods. Overall, 377 first-ever stroke patients were analyzed in this study period; men accounted for 59.2%. Compared with 2019, the incidence of first-ever stroke was 73.5% lower in 2020 ( < 0.001). The incidence of first-ever stroke was lower by 64.18% in 2020 than in the previous 5 years ( = 0.002) and by 65.42% in 2020 than in the previous 10 years ( = 0.001). Mortality from first-ever stroke in 2020 was not significantly different from that in 2019, but it was noticeably lower than that for the previous 5 and 10 years. However, rates of hospitalization and diagnosis by neuroimaging remained stable across the study period. These findings suggest that the home quarantine helped reduce outdoor activities at low temperatures, restrict gatherings, reduce alcoholism and high-fat diet, and lower pollution caused by factories. These changes were advantageous for helping high-risk groups to reduce the burden of stroke.
本研究旨在探讨2019冠状病毒病大流行期间与居家隔离相关的中风负担趋势。纳入了2010年至2020年1月1日至4月20日期间首次发生中风的患者。我们比较了研究期间中国农村低收入人群首次中风的发病率、死亡率、住院率和神经影像学诊断率。总体而言，本研究期间共分析了377例首次中风患者；男性占59.2%。与2019年相比，2020年首次中风的发病率降低了73.5%（<0.001）。2020年首次中风的发病率比前5年降低了64.18%（=0.002），比前10年降低了65.42%（=0.001）。2020年首次中风的死亡率与2019年无显著差异，但明显低于前5年和前10年。然而，在整个研究期间，住院率和神经影像学诊断率保持稳定。这些发现表明，居家隔离有助于减少低温下的户外活动、限制聚会、减少酗酒和高脂饮食，并降低工厂造成的污染。这些变化有利于帮助高危人群减轻中风负担。
