Talukder R K, Uddin M J, Battacharjee M, Akhter H, Pandit H, Pandit P, Rouf M A, Islam M S, Khan A M, Chowdhury R N, Ahammed S U, Hossain M B, Rahman K M, Kamrul-Hasan A B, Faysal M M, Saha G, Khan M M
Dr Mohammad Rezaul Karim Talukder, Assistant Professor, Department of Neurology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh.
Mymensingh Med J. 2018 Oct;27(4):685-692.
Stroke is leading cause of death world wide, after coronary artery disease and cancer. A high proportion of patients suffering from an acute stress such as stroke or myocardial infarction may develop hyperglycemia, even in the absence of a preexisting diagnosis of diabetes. An observational comparative study was carried out at the Department of Neurology and Medicine, Mymensingh Medical College, Mymensingh, Bangladesh from July 2011 to June 2013 among purposively selected ninety-three patients with a view to assess the outcome of stress hyperglycemia on acute stroke. Data were collected through interview, physical examinations & laboratory investigations by using case record form. Statistical analysis was performed using SPSS (Statistical package for social science) version 17. The mean age of this study was 59.04±15.01 years in the hyperglycemic group and 62.06±13.81 years in the normoglycemic group. The male female ratio in the Hyperglycemic and normoglycemic group was 2.12:1 and 2.44:1 respectively. Smoker was 48.8% in the hyperglycemic group and 52% in the normoglycemic group. 70% of the Hyperglycemic group and 66% of the normoglycemic were found hypertensive. Mean±SD blood glucose level was found 11.86±0.58mmol/L in the Hyperglycemic group and 6.50±1.55mmol/L in the normoglycemic group. Mean HbAlc were 6.14±0.56 in hyperglycemic group and 5.29±0.54 in normoglycemic group. Stroke severity score were 21.79±11.85 in Hyperglycemic and 28.64±9.53 in normoglycemic group on admission. Functional outcome was measured on discharge & at the end of 4th weeks of every patient by Glasgo Outcome Scale (GOS). The study also suggests that stress hyperglycemia is an important risk factor of poor stroke outcome.
中风是全球仅次于冠状动脉疾病和癌症的主要死因。即使在先前没有糖尿病诊断的情况下，很大一部分遭受中风或心肌梗死等急性应激的患者也可能出现高血糖。2011年7月至2013年6月，在孟加拉国迈门辛市迈门辛医学院神经科和内科进行了一项观察性比较研究，目的是评估应激性高血糖对急性中风的影响。通过使用病例记录表，通过访谈、体格检查和实验室检查收集数据。使用SPSS（社会科学统计软件包）17版进行统计分析。高血糖组的平均年龄为59.04±15.01岁，正常血糖组为62.06±13.81岁。高血糖组和正常血糖组的男女比例分别为2.12:1和2.44:1。高血糖组吸烟者占48.8%，正常血糖组吸烟者占52%。高血糖组70%的患者和正常血糖组66%的患者患有高血压。高血糖组的平均血糖水平为11.86±0.58mmol/L，正常血糖组为6.50±1.55mmol/L。高血糖组的平均糖化血红蛋白为6.14±0.56，正常血糖组为5.29±0.54。入院时，高血糖组的中风严重程度评分为21.79±11.85，正常血糖组为28.64±9.53。每位患者出院时及第4周结束时，通过格拉斯哥预后量表（GOS）测量功能预后。该研究还表明，应激性高血糖是中风预后不良的一个重要危险因素。
