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重复神经刺激试验在重症肌无力危象中的应用。

Repetitive nerve stimulation test in myasthenic crisis.

机构信息

Department of Neurology, University of Alabama at Birmingham, UAB Station, Birmingham, Alabama, 35294, USA.

Department of Neurology College of Medicine Soonchunhayng University, Cheonan, Republic of Korea.

出版信息

Muscle Nerve. 2019 May;59(5):544-548. doi: 10.1002/mus.26390. Epub 2019 Jan 9.

Abstract

INTRODUCTION

Herein we report our experience with the repetitive nerve stimulation (RNS) test in myasthenia gravis (MG) crisis.

METHODS

The various parameters of the RNS tests in 26 patients with MG crisis were analyzed.

RESULTS

In 18 (69%) patients, MG crisis is the first manifestation of MG. RNS tests were abnormal in 24 (92%) patients by decrement at low-rate stimulation in any of 4 tested muscles. Three patterns of abnormality were found: MG pattern (decrement at low-rate stimulation) in 23 patients; Lambert-Eaton myasthenic syndrome pattern in 1 patient; and cholinergic crisis pattern in 1 patient.

DISCUSSION

During MG crisis, the RNS test can serve as a rapid and sensitive diagnostic tool for MG in a majority of patients. Muscle Nerve 59:544-544, 2019.

摘要

简介

本文报告了我们在重症肌无力(MG)危象中重复神经刺激(RNS)测试的经验。

方法

分析了 26 例 MG 危象患者的 RNS 测试的各项参数。

结果

18 例(69%)患者的 MG 危象是 MG 的首发表现。24 例(92%)患者在 4 个受检肌肉中的任何一个肌肉以低频刺激时均出现递减,RNS 测试异常。发现了 3 种异常模式:23 例为 MG 模式(低频刺激时递减);1 例为 Lambert-Eaton 肌无力综合征模式;1 例为胆碱能危象模式。

讨论

在 MG 危象期间,RNS 测试可以作为大多数患者的快速、敏感的 MG 诊断工具。《神经肌肉疾病》59:544-544,2019。

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