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An insect brain peptide as a member of insulin family.

作者信息

Ishizaki H, Suzuki A

机构信息

Biological Institute, Faculty of Science, Nagoya University, Japan.

出版信息

Horm Metab Res. 1988 Jul;20(7):426-9. doi: 10.1055/s-2007-1010852.

DOI:10.1055/s-2007-1010852
PMID:3049291
Abstract

Amino acid sequencing of bombyxin (previously called 4K-PTTH) isolated from the heads of the silkmoth Bombyx mori has disclosed sequence homology of this insect neuropeptide with insulin. Immunohistochemistry using an antibody against a synthetic bombyxin fragment detected 4 pairs of immunoreactive neurosecretory cells in the dorso-medial region of the Bombyx brain. The same cells were reactive to bovine insulin antibody.

摘要

相似文献

1
An insect brain peptide as a member of insulin family.
Horm Metab Res. 1988 Jul;20(7):426-9. doi: 10.1055/s-2007-1010852.
2
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Cell Tissue Res. 1992 Jul;269(1):133-40. doi: 10.1007/BF00384733.

引用本文的文献

1
Insulin-like molecules in the beetle Tenebrio molitor.黄粉虫中的胰岛素样分子。
Cell Tissue Res. 1993 Jul;273(1):71-7. doi: 10.1007/BF00304613.
2
Structure and organization of four clustered genes that encode bombyxin, an insulin-related brain secretory peptide of the silkmoth Bombyx mori.编码家蚕素(一种与家蚕Bombyx mori脑分泌胰岛素相关的肽)的四个成簇基因的结构与组织
Proc Natl Acad Sci U S A. 1989 Sep;86(18):6843-7. doi: 10.1073/pnas.86.18.6843.
3
Determination of disulfide bond arrangement in bombyxin-IV, an insulin superfamily peptide from the silkworm, Bombyx mori, by combination of thermolysin digestion of natural peptide and selective synthesis of disulfide bond isomers.
通过天然肽的嗜热菌蛋白酶消化与二硫键异构体的选择性合成相结合的方法,确定家蚕胰岛素超家族肽家蚕素-IV中的二硫键排列。
J Protein Chem. 1992 Feb;11(1):13-20. doi: 10.1007/BF01025087.
4
Synthesis of bombyxin-IV, an insulin superfamily peptide from the silkworm, Bombyx mori, by stepwise and selective formation of three disulfide bridges.
J Protein Chem. 1992 Feb;11(1):1-12. doi: 10.1007/BF01025086.