The insulin receptor and the molecular mechanism of insulin action.
作者信息
Kahn C R, White M F
机构信息
Joslin Diabetes Center, Brigham and Women's Hospital, Boston, MA 02215.
出版信息
J Clin Invest. 1988 Oct;82(4):1151-6. doi: 10.1172/JCI113711.
Abstract
摘要
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本文引用的文献
1
2
Reversibility of the insulin-stimulated phosphorylation of ATP citrate lyase and a cytoplasmic protein of subunit Mr 22000 in adipose tissue.脂肪组织中胰岛素刺激的ATP柠檬酸裂解酶及一种22000亚基细胞质蛋白磷酸化的可逆性。
Biochem J. 1982 Apr 15;204(1):345-52. doi: 10.1042/bj2040345.
3
Decreased insulin binding in cultured lymphocytes from two patients with extreme insulin resistance.两名极端胰岛素抵抗患者培养淋巴细胞中胰岛素结合减少。
J Clin Endocrinol Metab. 1982 May;54(5):919-30. doi: 10.1210/jcem-54-5-919.
4
Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor.胰岛素刺激其自身受体95,000道尔顿亚基的磷酸化。
Science. 1982 Jan 8;215(4529):185-7. doi: 10.1126/science.7031900.
5
Studies on the incorporation of [32P]phosphate into pyruvate dehydrogenase in intact rat fat-cells. Effects of insulin.关于[32P]磷酸盐掺入完整大鼠脂肪细胞中丙酮酸脱氢酶的研究。胰岛素的作用。
Biochem J. 1980 Nov 15;192(2):469-81. doi: 10.1042/bj1920469.
6
Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries.具有独特亚基化学计量比的三种主要胰岛素受体结构的电泳分离。
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7137-41. doi: 10.1073/pnas.77.12.7137.
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Characterization of purified insulin receptor subunits.纯化胰岛素受体亚基的特性分析。
J Biol Chem. 1984 Jan 25;259(2):1206-11.
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Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes.3T3-L1脂肪细胞中的潜在胰岛素受体及可能的受体前体
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Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.胰岛素受体β亚基的酪氨酸磷酸化激活了受体相关的酪氨酸激酶活性。
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