Institute for Health Services Research and Health Economics, Centre for Health and Society, Faculty of Medicine, Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40255, Düsseldorf, Germany.
Institute for Health Services Research and Health Economics, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Syst Rev. 2018 Nov 29;7(1):214. doi: 10.1186/s13643-018-0884-5.
The 20-70% participation of diabetes patients in lifestyle interventions (LSI) worldwide seems to be rather sub-optimal, in spite of all intents of such interventions to delay further progress of the disease. Positive effects through LSI are expected in particular for patients who suffer less from diabetes-related limitations or other chronic diseases. Seeing that diabetes prevalence and with it mortality are increasing, LSI have become an inherent part of diabetes treatment standards. Various qualitative studies have been carried out to identify participation barriers for LSI. However, these have not resulted in more detailed knowledge about the relative importance of factors with an inhibiting impact on participation. Since it cannot be assumed that all of the influencing factors have equivalent values, it is necessary to investigate their individual importance with regard to a positive or negative decision about participating. There are no systematic reviews on patient preferences for LSI programs in diabetes prevention. As a result, the main objectives of this systematic review are to (i) identify existing patient preference elicitation studies related to LSI for diabetic patients, (ii) summarize the methods applied and findings, and (iii) appraise the reporting and methodological quality of such studies.
We will perform systematic literature searches to identify suitable studies from 14 electronic databases. Retrieved study records will be included based on predefined eligibility criteria as defined in this protocol. We will run abstract and full-text screenings and then extract data from all selected studies by filling in a predefined data extraction spreadsheet. We will undertake a descriptive, narrative synthesis of findings to address the study objectives, since no pooling for quantified preferences is for methodological reasons implementable. We will pay special attention to aspects of methodological quality of preference elicitation by applying established evaluation criteria of the ISPOR and some own developed criteria for different elicitation techniques. All critical stages within the screening, data extraction, and synthesis processes will be conducted by two pairs of authors. This protocol adheres to PRISMA and PRISMA-P standards.
The proposed systematic review will provide an overview of the methods used and current practice in the elicitation and quantification of patients' preferences for diabetes prevention lifestyle interventions. Furthermore, the methodological quality of the identified studies will be appraised as well.
PROSPERO CRD42018086988.
尽管生活方式干预（LSI）旨在延缓疾病的进一步进展，但全球范围内仅有 20-70%的糖尿病患者参与其中，这似乎还远远不够。LSI 有望对那些受糖尿病相关限制或其他慢性疾病影响较小的患者产生积极影响。鉴于糖尿病的患病率及其死亡率不断上升，LSI 已成为糖尿病治疗标准的固有组成部分。已经进行了各种定性研究以确定 LSI 的参与障碍。但是，这些研究并未深入了解对参与产生抑制作用的因素的相对重要性。由于不能假定所有影响因素都具有同等价值，因此有必要针对参与的积极或消极决策来研究它们各自的重要性。没有关于糖尿病预防中 LSI 计划患者偏好的系统评价。因此，本系统评价的主要目的是：（i）确定与糖尿病患者 LSI 相关的现有患者偏好 elicitation 研究，（ii）总结所应用的方法和发现，以及（iii）评估此类研究的报告和方法学质量。
我们将从 14 个电子数据库中进行系统的文献检索，以确定适合的研究。根据本方案中定义的预设纳入标准，将检索到的研究记录纳入研究。我们将进行摘要和全文筛选，然后通过填写预定义的数据提取电子表格从所有选定的研究中提取数据。由于出于方法学原因无法实施量化偏好的汇总，因此我们将对研究结果进行描述性的叙述性综合，以解决研究目标。我们将特别注意偏好 elicitation 的方法学质量方面，应用 ISPOR 的既定评估标准和针对不同 elicitation 技术的一些自己开发的标准。所有筛选，数据提取和综合过程的关键阶段都将由两对作者进行。本方案符合 PRISMA 和 PRISMA-P 标准。
拟议的系统评价将提供有关糖尿病预防生活方式干预中患者偏好 elicitation 和量化方法的概述。此外，还将评估所确定研究的方法学质量。
PROSPERO CRD42018086988。
