Centre for Population Health Sciences (CePHaS), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Dermatology, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Ann Epidemiol. 2019 Jan;29:8-15. doi: 10.1016/j.annepidem.2018.10.005. Epub 2018 Nov 12.
Chronic wounds are a major public health challenge, but little is known about the true burden with studies reporting different estimates because of disparities in study designs and measurement methods. This hampers efficient resource allocation, planning, and improvement of wound care.
Our study aimed to pool prevalence estimates from a global perspective by systematically carrying out searches in MEDLINE, EMBASE, Cochrane, CINAHL, Global Health, and PsycINFO databases for articles reporting the prevalence of chronic wounds in adults, from January 2000 to June 2018. The included publications had to define wound chronicity by duration (≥3 weeks), and/or labeling the wounds as chronic, complex, or hard-to-heal.
Seventeen studies met the inclusion criteria, and 11 studies analyzing chronic wounds in the general population were included in random effects meta-analyses to calculate pooled prevalence. Chronic wounds of mixed etiologies (n = 3) showed a pooled prevalence of 2.21 per 1000 population, and for chronic leg ulcers (n = 9), the prevalence was estimated at 1.51 per 1000 population.
Our findings, aligned to previous studies reporting point prevalence of chronic wounds identified within the healthcare system, showed that the vast majority of chronic wounds in epidemiological studies are made up by chronic leg ulcers.
慢性伤口是一个主要的公共卫生挑战,但由于研究设计和测量方法的差异,研究报告的估计值不同,因此对其实际负担知之甚少。这阻碍了资源的有效分配、规划以及伤口护理的改进。
本研究旨在通过在 MEDLINE、EMBASE、Cochrane、CINAHL、全球健康和 PsycINFO 数据库中系统地进行检索,从全球角度汇总患病率估计值,以检索报告 2000 年 1 月至 2018 年 6 月期间成年人慢性伤口患病率的文章。纳入的文献必须通过持续时间(≥3 周)定义伤口的慢性,和/或将伤口标记为慢性、复杂或难以愈合。
有 17 项研究符合纳入标准,其中 11 项分析了普通人群中的慢性伤口,这些研究被纳入随机效应荟萃分析,以计算汇总患病率。混合病因的慢性伤口(n=3)的患病率为每 1000 人 2.21,慢性腿部溃疡(n=9)的患病率估计为每 1000 人 1.51。
我们的研究结果与之前报告的在医疗保健系统内确定的慢性伤口点患病率的研究一致,表明在流行病学研究中,绝大多数慢性伤口是由慢性腿部溃疡组成的。