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慢性伤口及其相关并发症的患病率和发病率:一项系统评价方案

Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review.

作者信息

Järbrink Krister, Ni Gao, Sönnergren Henrik, Schmidtchen Artur, Pang Caroline, Bajpai Ram, Car Josip

机构信息

Centre for Population Health Sciences (CePHaS), Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Experimental Medicine Building, Singapore, 636921, Singapore.

Department of Dermatology, Skåne University Hospital, Lasarettsgatan 15, 221 85, Lund, Sweden.

出版信息

Syst Rev. 2016 Sep 8;5(1):152. doi: 10.1186/s13643-016-0329-y.

Abstract

BACKGROUND

Chronic wounds impose a significant and often underappreciated burden to the individual, the healthcare system and the society as a whole. Preliminary literature search suggests that there are at present no reliable estimates on the total prevalence of chronic wounds for different settings and categories of chronic wounds. Such information is essential for policy and planning purposes as the increasing number of elderly and the prevalence of lifestyle diseases point in the direction of an increased burden. Knowledge about the prevalence and incidence of chronic wounds in relation to population characteristics is important for informing healthcare planning and resource allocation. The objective is to present a transparent process for how to review the existing literature on the prevalence and incidence rates of chronic wounds and resulting implications.

METHODS/DESIGN: We will search electronic bibliographic databases (MEDLINE, EMBASE, the EBM Reviews and Cochrane, Cumulative Index to Nursing and allied Health Literature (CINAHL), PsycINFO, Global Health) and reference lists of included articles. Two investigators will independently screen titles and abstracts and select studies involving adults with chronic wounds. These investigators will also independently extract data using a pre-designed data extraction form that will cover information on demographics, diagnostics including disease prevalence, medical history, hospital and community-based management and outcomes. Subgroup analysis and sensitivity analysis will be performed to address the heterogeneity across studies. Meta-analysis will also be performed if homogeneous group of studies will be found. The collective evidence will be further stratified according to the important background variables if allowed.

DISCUSSION

This study will describe the available epidemiological evidence and summarise prevalence and incidence rates of chronic wounds and related complications. A better understanding of the relationship between population profile and the prevalence of chronic wounds and related complications will be helpful in the development of guidelines for patient management.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO CRD42016037355.

摘要

背景

慢性伤口给个人、医疗保健系统乃至整个社会带来了重大且往往未得到充分重视的负担。初步文献检索表明,目前尚无针对不同环境和慢性伤口类别的慢性伤口总患病率的可靠估计。由于老年人数量的增加以及生活方式疾病的流行预示着负担的加重,此类信息对于政策制定和规划目的至关重要。了解慢性伤口的患病率和发病率与人口特征之间的关系,对于指导医疗保健规划和资源分配具有重要意义。目的是展示一个透明的过程,说明如何回顾关于慢性伤口患病率和发病率的现有文献及其产生的影响。

方法/设计:我们将检索电子文献数据库(MEDLINE、EMBASE、循证医学评价数据库和Cochrane数据库、护理学与健康相关文献累积索引(CINAHL)、心理学文摘数据库(PsycINFO)、全球健康数据库)以及纳入文章的参考文献列表。两名研究人员将独立筛选标题和摘要,并选择涉及患有慢性伤口的成年人的研究。这些研究人员还将使用预先设计的数据提取表独立提取数据,该表将涵盖人口统计学信息、诊断信息(包括疾病患病率)、病史、基于医院和社区的管理以及结果。将进行亚组分析和敏感性分析,以解决各研究之间的异质性问题。如果发现研究组具有同质性,也将进行荟萃分析。如有可能,将根据重要的背景变量对汇总证据进行进一步分层。

讨论

本研究将描述现有的流行病学证据,并总结慢性伤口及其相关并发症的患病率和发病率。更好地理解人口特征与慢性伤口及其相关并发症患病率之间的关系,将有助于制定患者管理指南。

系统评价注册

PROSPERO CRD42016037355。

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