Harrington Kate Anne, Hoda Syed, La Rocca Vieira Renata
Department of Musculoskeletal Radiology, NYU Langone Health, New York, NY, USA.
Department of Pathology, NYU Langone Health, New York, NY, USA.
Skeletal Radiol. 2019 May;48(5):823-830. doi: 10.1007/s00256-018-3120-4. Epub 2018 Nov 29.
Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm that typically occurs in young adults. Juxtacortical or surface-type CMF are rarer still and we present the case of a surface-type CMF in a 78-year-old woman, with only one other case described in a patient of a similar age previously. This patient was an otherwise healthy woman who presented for evaluation of a palpable lump in the anterior proximal tibia. Initial radiographs obtained demonstrated a focal soft tissue fullness immediately anterior to the anterior cortex of the proximal tibia, which contained faint chondroid-like matrix internally. There was associated scalloping of the anterior tibial cortex. MRI confirmed the presence of a juxtacortical, enhancing lesion. Subsequent excisional biopsy was performed and histopathology demonstrated features, which was consistent with surface-type CMF. At a 6-month follow-up the patient remained free of recurrence. In a patient of this age, paraosteal chondrosarcoma should be excluded. Surface-type CMF, although rare, has been described in older patients and while it is unlikely to feature in a list of differential considerations on initial imaging, awareness of the entity is important.
软骨黏液样纤维瘤(CMF)是一种罕见的良性骨肿瘤,通常发生于年轻人。皮质旁型或表面型CMF更为罕见,我们报告了一例78岁女性的表面型CMF病例,此前仅有一例年龄相仿患者的病例报道。该患者为一名健康女性,因胫骨近端前侧可触及肿块前来评估。最初的X线片显示胫骨近端前皮质前方有局灶性软组织饱满,内部含有模糊的软骨样基质。胫骨前皮质有相关的扇贝样改变。MRI证实存在皮质旁强化病变。随后进行了切除活检,组织病理学显示的特征符合表面型CMF。在6个月的随访中,患者无复发。对于这个年龄段的患者,应排除骨膜软骨肉瘤。表面型CMF虽然罕见,但在老年患者中已有报道,虽然在初始影像学检查的鉴别诊断中不太可能出现,但认识到这种疾病很重要。