Bubnova I A, Egorova G B, Mitichkina T S, Averich V V, Fettser E I
Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.
I.M. Sechenov First Moscow State Medical University, Chair of Ophthalmology, 8-2 Malaya Trubetskaya St., Moscow, Russian Federation, 119991.
Vestn Oftalmol. 2018;134(5. Vyp. 2):294-298. doi: 10.17116/oftalma2018134051294.
The article reviews the particularities of development and pathogenesis of secondary dry eye syndrome (DES) after refractive surgeries including a complex of problems related to changes in tear film content, damage of eye surface and neurotrophic epitheliopathy. Additionally, modern algorithms of treatment and prevention of secondary DES in patients after refractive surgeries are described. Despite the transient nature of the changes, excimer-laser surgery can lead to lasting deficiencies of eye surface in some patients. Therefore, intensive and early treatment of secondary DES during the early follow-up period after refractive surgery may significantly reduce risks of tear dysfunction and neurotrophic epitheliopathy development in the long term.
本文综述了屈光手术后继发性干眼综合征（DES）的发展特点和发病机制，包括与泪膜成分变化、眼表损伤和神经营养性上皮病变相关的一系列问题。此外，还描述了屈光手术后患者继发性DES的现代治疗和预防方案。尽管这些变化具有短暂性，但准分子激光手术仍可能导致部分患者出现持久的眼表缺陷。因此，在屈光手术后的早期随访期间对继发性DES进行强化和早期治疗，可能会在长期显著降低泪液功能障碍和神经营养性上皮病变的发生风险。
