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IgG subclass distribution of antinative type II collagen and antidenatured type II collagen antibodies in patients with rheumatoid arthritis.

作者信息

Collins I, Morgan K, Clague R B, Brenchley P E, Holt P J

机构信息

Department of Rheumatology, University of Manchester Medical School, UK.

出版信息

J Rheumatol. 1988;15(5):770-4.

PMID:3050082
Abstract

In 81 patients with rheumatoid arthritis (RA) with antibodies to native type II collagen, the frequencies of each IgG subclass to native type II collagen were IgG1 (70%), IgG2 (12%), IgG3 (84%) and IgG4 (6%) and to denatured type II collagen were IgG1 (86%), IgG2 (23%), IgG3 (86%) and IgG4 (6%). Thus serum antibodies to type II collagen in patients with RA were predominantly of the complement fixing subclasses IgG1 and IgG3.

摘要

相似文献

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Immune deposits in articular cartilage of patients with rheumatoid arthritis have a granular pattern not seen in osteoarthritis.类风湿性关节炎患者关节软骨中的免疫沉积物呈颗粒状，骨关节炎患者则未见此现象。
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What do anti-collagen antibodies mean?抗胶原蛋白抗体是什么意思？
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