Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
J Surg Res. 2019 Jan;233:413-419. doi: 10.1016/j.jss.2018.08.031. Epub 2018 Sep 18.
Resuscitative endovascular balloon occlusion of the aorta (REBOA) has emerged as a bridge to definitive hemostasis in select patients with noncompressible torso hemorrhage. The number of patients who might benefit from this procedure, however, remains incompletely defined. We hypothesized that we could quantify the number of patients presenting to our center over a 2-year period who may have benefited from REBOA.
All patients presenting to our trauma center from 2014 to 2015 were included. Potential REBOA patients were identified based on anatomic injuries. We used ICD-9 codes to identify REBOA-amenable injury patterns and physiology. We excluded patients with injuries contraindicating REBOA. We then used chart review by two REBOA-experienced independent reviewers to assess each potential REBOA candidate, evaluate the accuracy of our algorithm, and to identify a cohort of confirmed REBOA candidates.
Four thousand eight hundred eighteen patients were included of which 666 had injuries potentially amenable to REBOA. Three hundred thirty-five patients were hemodynamically unstable, and 309 patients had contraindications to REBOA. Sixty-four patients had both injury patterns and physiology amenable to REBOA with no contraindications, and these patients were identified as potential REBOA candidates. Of these, detailed independent two physician chart review identified 29 patients (45%) as confirmed REBOA candidates (interrater reliability kappa = 0.94, P < 0.001).
Our database query identified patients with indications for REBOA but overestimated the number of REBOA candidates. To accurately quantify the REBOA candidate population at a given center, an algorithm to identify potential patients should be combined with chart review.
Therapeutic study, level V.
在某些非压缩性躯干出血的患者中,主动脉球囊阻断复苏术(REBOA)已成为明确止血的桥梁。然而,受益于该手术的患者数量仍不完全明确。我们假设可以对 2 年内到我们中心就诊的可能受益于 REBOA 的患者数量进行量化。
纳入 2014 年至 2015 年期间到我们创伤中心就诊的所有患者。根据解剖损伤确定潜在的 REBOA 患者。我们使用 ICD-9 编码来识别适合 REBOA 的损伤模式和生理特征。排除禁忌 REBOA 的患者。然后,我们使用两位具有 REBOA 经验的独立审查员进行图表审查,以评估每位潜在的 REBOA 候选者,评估我们的算法的准确性,并确定一组经过证实的 REBOA 候选者。
共纳入 4818 名患者,其中 666 名患者的损伤可能适合 REBOA。335 名患者血流动力学不稳定,309 名患者有 REBOA 禁忌证。64 名患者既有损伤模式又有适合 REBOA 的生理特征且无禁忌证,这些患者被认为是潜在的 REBOA 候选者。在这些患者中,详细的独立的两位医生图表审查确定了 29 名患者(45%)为经证实的 REBOA 候选者(两位审查者间的可靠性 κ=0.94,P<0.001)。
我们的数据库查询确定了适合 REBOA 的患者,但高估了 REBOA 候选者的数量。为了准确量化特定中心的 REBOA 候选人群,应将识别潜在患者的算法与图表审查相结合。
治疗性研究,五级。