Pulmonology Department, Hospital Santa Maria Maior, Barcelos, Portugal.
Chest Department, Centro Hospitalar Lisboa Norte, Lisbon, Portugal; Environmental Health Institute (ISAMB), Faculty of Medicine, University of Lisbon, Portugal.
Pulmonology. 2019 Mar-Apr;25(2):90-96. doi: 10.1016/j.pulmoe.2018.10.005. Epub 2018 Nov 28.
Chronic Obstructive Pulmonary Disease (COPD) is currently the 4th leading cause of death worldwide but is projected to be the 3rd leading cause of death by 2020. In Portugal, the estimated prevalence of COPD in the Lisbon region is 14.2%, and a large proportion of underdiagnosed disease has been detected. In 2016, a Portuguese panel of experts proposed pharmacological treatment approaches to COPD based on the evidence available at the time. However, given that the GOLD 2017 report introduced considerable changes to the 2016 version, and that new evidence has emerged regarding treatment options, these proposals need to be updated. Also, and based on several studies, the concept of Pre-GOLD patients, which has diagnostic, prognostic and therapeutic implications, is introduced, along with a proposed algorithm for the identification and treatment of these patients.
慢性阻塞性肺疾病（COPD）目前是全球第 4 大死亡原因，但预计到 2020 年将成为第 3 大死亡原因。在葡萄牙，里斯本地区估计 COPD 的患病率为 14.2%，并且已经发现了很大一部分未被诊断的疾病。2016 年，一个葡萄牙专家小组根据当时的可用证据提出了 COPD 的药物治疗方法。然而，鉴于 GOLD 2017 报告对 2016 年版本进行了重大修改，并且出现了关于治疗选择的新证据，因此需要对这些建议进行更新。此外，基于几项研究，引入了具有诊断、预后和治疗意义的 Pre-GOLD 患者概念，并提出了一种用于识别和治疗这些患者的算法。
