Requena Caballero L, Sánchez López M, Requena Caballero C, Vázquez López F, Hernández Moro B
Servicio de Dermatología, Hospital Militar Central Gómez-Ulla, Madrid.
Med Cutan Ibero Lat Am. 1988;16(2):106-10.
We report a case of a previously diagnosed patient of Hodgkin's disease, nodular sclerosis type and IVLDB stage. This patient subsequently presented a dermatologic nodule. A specimen cutaneous biopsy was performed and the histopathologic study demonstrated a dermal infiltrate with many classic Reed-Sternberg giant cells. These findings were consistent with the skin involvement in Hodgkin's disease. Specific cutaneous lesions are rare in this lymphoma and therefore it may be argued that our patient had a lymphomatoid papulosis. However, the protracted clinical course would not support this concept, because the dermatologic lesion responded to chemotherapy and it is well-known that the clinical course of the lymphomatoid papulosis is unaffected by these treatments. We concluded that our patient is a case of specific skin involvement in Hodgkin's disease.
我们报告一例先前诊断为结节硬化型霍奇金病且处于IVLDB期的患者。该患者随后出现了一个皮肤结节。进行了皮肤活检标本检查，组织病理学研究显示真皮浸润，有许多典型的里德-斯腾伯格巨细胞。这些发现与霍奇金病的皮肤受累情况相符。这种淋巴瘤中特异性皮肤病变罕见，因此可以认为我们的患者患有淋巴瘤样丘疹病。然而，病程迁延不支持这一观点，因为皮肤病变对化疗有反应，而且众所周知，淋巴瘤样丘疹病的临床病程不受这些治疗的影响。我们得出结论，我们的患者是霍奇金病特异性皮肤受累的病例。
