Cernea P, Szpirglas H, Brocheriou C, Guilbert F, Bertrand C, Vaillant J M, Tereau Y, Cayron R, Krivine F, Nezelof C, Iris L, Binet J L, Raphael M, Le Porier M, Chenal C, Caubarere I
Rev Stomatol Chir Maxillofac. 1978;79(2):99-107.
A case of Hodgkin's disease beginning in the skin of the face with local lymph node involvement is reported. This was a lymphogranulomatous form without characteristic Reed-Sternberg cells in skin biopsy specimens, rendering the diagnosis difficult. There was a combination of granulomatous inflammation, plaques of necrosis and lesions of fibrinoid necrosis in the vessel walls. This form entered the classification of clinical Stage IV, with its associated serious prognosis.
报告了一例始于面部皮肤并伴有局部淋巴结受累的霍奇金病病例。这是一种淋巴肉芽肿形式,皮肤活检标本中没有特征性的里德-斯腾伯格细胞,这使得诊断困难。存在肉芽肿性炎症、坏死斑块以及血管壁的纤维素样坏死病变。这种形式进入了临床IV期分类,其预后严重。