Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
J Shoulder Elbow Surg. 2019 Mar;28(3):453-460. doi: 10.1016/j.jse.2018.08.036. Epub 2018 Nov 29.
Recent orthopedic research has questioned the effect of opioid use on surgical outcomes. This study investigated this in the context of arthroscopic rotator cuff repair. We hypothesized that preoperative opioid use would be associated with inferior outcomes and greater postoperative opioid requirements.
A database query identified adult patients with full-thickness or partial-thickness supraspinatus tears surgically treated between 2011 and 2015. Preoperative and postoperative outcomes scores (active range of motion [AROM], American Shoulder and Elbow Surgeons [ASES], Constant scores, Simple Shoulder Test [SST], and visual analog scale [VAS] for pain) and postoperative opioid use were retrospectively recorded. Patients with less than 2 years of follow-up data at the time of the retrospective review were contacted for prospective ASES, SST, and VAS data collection.
A total of 200 patients, 44 of whom received opioids preoperatively, were identified for inclusion. Patients prescribed preoperative opioids had consistently inferior preoperative and postoperative outcomes scores; however, the magnitudes of improvement were not significantly different between groups. Postoperatively, patients in the preoperative opioid group received 1.91 (95% confidence interval, 1.31-2.78) times more opioids over a postoperative course of treatment that was 2.73 (95% confidence interval, 1.62-4.59) times longer. In addition to having a greater proportion of women, this group also had significantly higher rates of certain comorbidities, including back pain, depression, degenerative joint disease, and chronic pain conditions.
All patients demonstrated significant improvements in outcomes scores after surgical repair that were not significantly different between groups. However, patients taking opioids preoperatively did not ultimately reach the same level of functionality and had substantially greater opioid requirements postoperatively.
最近的骨科研究对阿片类药物的使用对手术结果的影响提出了质疑。本研究在关节镜肩袖修复的背景下对此进行了调查。我们假设术前使用阿片类药物与较差的结果和术后阿片类药物需求增加有关。
数据库查询确定了 2011 年至 2015 年间接受全层或部分冈上肌腱撕裂手术治疗的成年患者。回顾性记录术前和术后结果评分(主动活动范围[AROM]、美国肩肘外科医生协会[ASES]、Constant 评分、简单肩部测试[SST]和疼痛视觉模拟评分[VAS])和术后阿片类药物的使用情况。在回顾性审查时,对随访数据少于 2 年的患者进行联系,以收集前瞻性 ASES、SST 和 VAS 数据。
共确定了 200 名患者,其中 44 名患者术前接受了阿片类药物治疗。接受术前阿片类药物治疗的患者术前和术后的结果评分均较差;然而,两组之间的改善幅度没有显著差异。术后,术前阿片类药物组的患者在术后治疗过程中接受了 1.91 倍(95%置信区间,1.31-2.78)的阿片类药物,而治疗时间延长了 2.73 倍(95%置信区间,1.62-4.59)。除了女性比例较高外,该组还具有较高的某些合并症发生率,包括背痛、抑郁症、退行性关节病和慢性疼痛疾病。
所有患者在手术修复后,结果评分均有显著改善,两组间无显著差异。然而,术前服用阿片类药物的患者最终并未达到相同的功能水平,并且术后阿片类药物的需求明显增加。