São Paulo State University (UNESP), Institute of Biosciences, Praça Infante Dom Henrique, s/n, Parque Bitaru, São Vicente, SP, Brazil..
São Paulo State University (UNESP), Institute of Biosciences, Praça Infante Dom Henrique, s/n, Parque Bitaru, São Vicente, SP, Brazil.
Mar Pollut Bull. 2018 Dec;137:711-722. doi: 10.1016/j.marpolbul.2018.11.015. Epub 2018 Nov 15.
The gastrointestinal tract (GIT) of fish is a target of contaminants since it can absorb these substances. We evaluated the morphophysiological alterations in the GIT of Sphoeroides testudineus collected in two estuaries presenting differences in their environmental quality (NIA and IA). The intestine was analyzed for histological and neuronal changes; liver and gills for biochemical markers; muscle tissues for neurotoxicity and peripheral blood for genotoxic damage. The results showed alterations in the GIT of the animals collected in the IA, such as muscle tunica and goblet cell density reduction, increased intraepithelial lymphocytes density and changes in neuronal density. Furthermore, changes were observed in MTs and LPO in the gills. Thus, we suggest that TGI is functioning as a barrier that responds to ingested contaminants, in order to reduce their absorption and translocation. Thus, alterations in morphophysiological and enteric neurons in S. testudineus can be used as biomarkers of environmental contamination.
鱼类的胃肠道（GIT）是污染物的靶标，因为它可以吸收这些物质。我们评估了在两个具有不同环境质量的河口（NIA 和 IA）中收集的 Sphoeroides testudineus 的 GIT 的形态生理学变化。对肠道进行组织学和神经元变化分析；肝脏和鳃用于生化标志物分析；肌肉组织用于神经毒性分析；外周血液用于遗传毒性损伤分析。结果表明，在 IA 中收集的动物的 GIT 发生了变化，例如肌肉层和杯状细胞密度降低，上皮内淋巴细胞密度增加以及神经元密度变化。此外，在鳃中还观察到 MT 和 LPO 的变化。因此，我们认为 TGI 作为屏障发挥作用，以减少其吸收和转移。因此，S. testudineus 的形态生理学和肠神经元的变化可用作环境污染的生物标志物。
