年轻人的饮食炎症指数与胰岛素抵抗或代谢综合征。

The dietary inflammatory index and insulin resistance or metabolic syndrome in young adults.

机构信息

Federal Institute of Maranhão, Collective Health Program, Federal University of Maranhão, São Luís, Maranhão, Brazil.

Postgraduate Program of Collective Health, Department of Public Health, Federal University of Maranhão.

出版信息

Nutrition. 2019 Feb;58:187-193. doi: 10.1016/j.nut.2018.07.014. Epub 2018 Aug 23.

DOI:10.1016/j.nut.2018.07.014

PMID:30504010

Abstract

OBJECTIVE

The aim of this study was to assess the association between the inflammatory potential of diet, as measured by the dietary inflammatory index (DII) and insulin resistance (IR) or metabolic syndrome (MetS).

METHODS

A cross-sectional study (nested within a cohort) was conducted on 2017 adults 23 to 25 y of age in Ribeirão Preto, Brazil. Food consumption was assessed using a validated food frequency questionnaire. DII scores were calculated from 35 available food parameters. IR was determined from the classification of homeostatic model assessment (HOMA) values (≥2.7 uU mL-1). MetS was diagnosed based on the Joint Interim Statement (JIS) criterion. The association of DII score with IR or MetS was determined by Poisson regression analysis. The variables included in the multivariable model were selected from directed acyclic graphs.

RESULTS

The diet of the young adults studied showed a high inflammatory potential, with a mean DII score of +1.10 (range: -4.69 to +5.28). The prevalence of MetS was 12.2% and IR 12.3%; both were higher in men than in women. The correlation between DII and HOMA-IR values was -0.038 (P = 0.09). The DII was not associated with IR or MetS in either sex.

CONCLUSION

Although the association between DII and the outcomes was not detected in this sample, the study demonstrated that the diets of these young adult Brazilians had a high inflammatory potential when compared with other studies. Future studies, preferably using longitudinal designs, are recommended.

摘要

目的

本研究旨在评估饮食炎症潜能（通过膳食炎症指数[DII]评估）与胰岛素抵抗（IR）或代谢综合征（MetS）之间的相关性。

方法

这是一项在巴西里贝朗普雷托进行的横断面研究（嵌套在队列研究中），研究对象为 2017 名年龄在 23 至 25 岁的成年人。采用经过验证的食物频率问卷评估食物摄入量。通过 35 种可用食物参数计算 DII 评分。IR 通过稳态模型评估（HOMA）值的分类来确定（≥2.7 uU mL-1）。MetS 根据联合临时声明（JIS）标准进行诊断。通过泊松回归分析确定 DII 评分与 IR 或 MetS 的相关性。多变量模型中包含的变量是从有向无环图中选择的。

结果

研究中年轻成年人的饮食具有较高的炎症潜能，平均 DII 得分为+1.10（范围：-4.69 至+5.28）。MetS 的患病率为 12.2%，IR 为 12.3%；男性高于女性。DII 与 HOMA-IR 值之间的相关性为-0.038（P=0.09）。DII 与 IR 或 MetS 在男女两性中均无相关性。