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Adoptive immunotherapy in conjunction with bone marrow transplantation--amplification of natural host defence mechanisms against cancer by recombinant IL-2.

作者信息

Slavin S, Eckerstein A, Weiss L

机构信息

Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel.

出版信息

Nat Immun Cell Growth Regul. 1988;7(3):180-4.

PMID:3050476
Abstract
摘要

相似文献

1
Adoptive immunotherapy in conjunction with bone marrow transplantation--amplification of natural host defence mechanisms against cancer by recombinant IL-2.过继性免疫疗法联合骨髓移植——通过重组白细胞介素-2增强宿主对抗癌症的天然防御机制
Nat Immun Cell Growth Regul. 1988;7(3):180-4.
2
Effective graft-versus-leukemia effects independent of graft-versus-host disease after T cell-depleted allogeneic bone marrow transplantation in a murine model of B cell leukemia/lymphoma. Role of cell therapy and recombinant IL-2.在B细胞白血病/淋巴瘤小鼠模型中，T细胞去除的异基因骨髓移植后，不依赖移植物抗宿主病的有效移植物抗白血病效应。细胞疗法和重组白细胞介素-2的作用
J Immunol. 1994 Sep 15;153(6):2562-7.
3
Selective inhibition of CD4 graft-versus-host activity in IL-2-treated mice.在白细胞介素-2治疗的小鼠中对CD4移植物抗宿主活性的选择性抑制。
Transplant Proc. 1993 Feb;25(1 Pt 2):1225-6.
4
Immunotherapy in conjunction with autologous bone marrow transplantation.免疫疗法联合自体骨髓移植。
Bone Marrow Transplant. 1990 Jan;5 Suppl 1:38.
5
Allogeneic cell therapy in murine B-cell leukemia (BCL1): 1. Alloimmune-mediated graft-versus-leukemia (GVL) effects induced by unmodified and in vitro rIL-2-activated bone marrow and lymphocytes from different lymphoid compartments.小鼠B细胞白血病（BCL1）中的异基因细胞疗法：1. 来自不同淋巴区室的未修饰和体外经重组白细胞介素-2激活的骨髓及淋巴细胞诱导的同种免疫介导的移植物抗白血病（GVL）效应。
Cytokines Cell Mol Ther. 1999 Sep;5(3):145-52.
6
Allogeneic cell-mediated immunotherapy of leukemia with immune donor lymphocytes to upregulate antitumor effects and downregulate antihost responses.利用免疫供体淋巴细胞对白血病进行异基因细胞介导的免疫治疗，以增强抗肿瘤作用并下调抗宿主反应。
Bone Marrow Transplant. 2003 Sep;32(5):495-504. doi: 10.1038/sj.bmt.1704150.
7
Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.异基因骨髓移植后活化自然杀伤细胞对移植物抗宿主病的抑制及对移植物抗肿瘤效应的增强
J Clin Invest. 1998 May 1;101(9):1835-42. doi: 10.1172/JCI1268.
8
Induction of early post-transplant graft-versus-leukemia effects using intentionally mismatched donor lymphocytes and elimination of alloantigen-primed donor lymphocytes for prevention of graft-versus-host disease.使用故意不匹配的供体淋巴细胞诱导移植后早期移植物抗白血病效应，并清除同种抗原致敏的供体淋巴细胞以预防移植物抗宿主病。
Cancer Res. 2005 Nov 1;65(21):9735-40. doi: 10.1158/0008-5472.CAN-04-4175.
9
The role of antibodies to IL-2 receptor and Asialo GM1 on graft-versus-leukemia effects induced by bone marrow allografts in murine B cell leukemia.抗白细胞介素-2受体抗体和去唾液酸神经节苷脂GM1在小鼠B细胞白血病骨髓同种异体移植诱导的移植物抗白血病效应中的作用
Bone Marrow Transplant. 1995 Sep;16(3):457-61.
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Adoptive cell-mediated immunotherapy with interleukin-2 (IL-2) for relapsing lymphoblastic crisis following mismatched unrelated bone marrow transplantation in a chronic myelogenous leukemia patient.
Bone Marrow Transplant. 1998 Jan;21(1):93-6. doi: 10.1038/sj.bmt.1701040.

引用本文的文献

1
Immunotherapy with cure potential of multi-drug resistant hematologic malignancies using IL-2 preactivated intentionally mismatched donor lymphocyte.采用 IL-2 预激活的故意错配供者淋巴细胞进行免疫治疗，具有治疗多药耐药性血液系统恶性肿瘤的潜力。
J Cancer Res Clin Oncol. 2023 Sep;149(11):9277-9284. doi: 10.1007/s00432-023-04780-5. Epub 2023 May 19.
2
Adoptive Immunotherapy For Leukemia With Ex vivo Expanded T Cells.采用体外扩增T细胞进行白血病的过继性免疫治疗。
Curr Drug Targets. 2017;18(3):271-280. doi: 10.2174/1389450117666160209143529.
3
Immunotherapy in high-risk chemotherapy-resistant patients with metastatic solid tumors and hematological malignancies using intentionally mismatched donor lymphocytes activated with rIL-2: a phase I study.
采用 IL-2 激活的故意错配供者淋巴细胞治疗化疗耐药的转移性实体瘤和血液恶性肿瘤高危患者的免疫疗法：一项 I 期研究。
Cancer Immunol Immunother. 2010 Oct;59(10):1511-9. doi: 10.1007/s00262-010-0878-1. Epub 2010 Jun 20.
4
Characterization of effector cells of graft vs leukemia following allogeneic bone marrow transplantation in mice inoculated with murine B-cell leukemia.在接种小鼠B细胞白血病的小鼠中进行同种异体骨髓移植后移植物抗白血病效应细胞的特征分析。
Cancer Immunol Immunother. 1990;31(4):236-42. doi: 10.1007/BF01789175.
5
Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells.白细胞介素2可预防移植物抗宿主病，同时保留同种异体T细胞的移植物抗白血病效应。
Proc Natl Acad Sci U S A. 1990 Aug;87(15):5633-7. doi: 10.1073/pnas.87.15.5633.
6
In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment.体内给予白细胞介素2加去除T细胞的同基因骨髓可预防移植物抗宿主病死亡并允许同种异体移植。
J Exp Med. 1990 Mar 1;171(3):645-58. doi: 10.1084/jem.171.3.645.