de Chavez R, Jones C E, Charles P H
Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia.
Science and Engineering Faculty, Queensland University of Technology, Brisbane, Australia.
Australas Phys Eng Sci Med. 2019 Mar;42(1):235-244. doi: 10.1007/s13246-018-0716-x. Epub 2018 Nov 30.
Previous studies describe the use of a large area parallel-plate chamber, the PTW Bragg Peak chamber, for measuring dose-area product (DAP) and output factors in small megavoltage photon fields. However, in radiotherapy departments without protons, this detector would have to be purchased separately for this purpose. This work investigated the feasibility of alternatively using a large transmission ionisation chamber, the IBA round Stealth chamber (SC), for output factor measurements of stereotactic fields. This type of detector is more commonly found in radiotherapy departments as a reference chamber for water tank scanning of small fields, and hence DAP could be performed without an additional purchase. The SC's large sensitive area (diameter of 94 mm) measures the integral dose, also known as DAP, over the whole two-dimensional (2D) dose distribution of the small field. The measurements were performed using a 6 MV beam from an Elekta Infinity linear accelerator. Conversion of DAP to central axis point dose was performed using 2D dose maps from Gafchromic EBT3 films. The field sizes measured ranged from side length of 5 mm to 50 mm (all square). The resultant output factors were compared against measurements with a stereotactic diode. The small field output factors measured using SC + film were in good agreement with the stereotactic diode (within 2% for field sizes as small as 6 mm; 3% difference at 5 mm). The new proposed method showed that a transmission chamber like SC is a good alternative large-area parallel plate chamber to measure DAP and derive small field OFs. Furthermore, the feasibility of using 2D reconstructed dose maps from water tank profiles and hence filmless approach was investigated. Results showed that filmless conversion of DAP to central axis point dose is feasible using profiles. However, a large number of profiles are required (i.e. 15° increments (star pattern) are required for accurate 2D dose reconstruction), and hence the water tank scanning for this approach may be prohibitively time-consuming.
以往的研究描述了使用大面积平行板电离室(PTW布拉格峰电离室)来测量小兆伏级光子射野中的剂量面积乘积(DAP)和输出因子。然而,在没有质子治疗设备的放疗科室,为此目的必须单独购买这种探测器。本研究探讨了另一种方法的可行性,即使用大型透射电离室(IBA圆形隐身电离室,SC)来测量立体定向射野的输出因子。这种类型的探测器在放疗科室更为常见,是用于小射野水箱扫描的参考电离室,因此无需额外购买就能进行DAP测量。SC的大灵敏面积(直径94毫米)可测量小射野整个二维剂量分布上的积分剂量,即DAP。测量使用的是Elekta Infinity直线加速器的6兆伏射线束。利用Gafchromic EBT3胶片的二维剂量图将DAP转换为中心轴点剂量。测量的射野尺寸范围为边长5毫米至50毫米(均为正方形)。将所得的输出因子与使用立体定向二极管测量的结果进行比较。使用SC + 胶片测量的小射野输出因子与立体定向二极管的测量结果吻合良好(对于小至6毫米的射野尺寸,误差在2%以内;在5毫米时差异为3%)。新提出的方法表明,像SC这样的透射电离室是测量DAP和推导小射野输出因子的一种很好的替代大面积平行板电离室。此外,还研究了从水箱轮廓使用二维重建剂量图从而实现无胶片方法的可行性。结果表明,使用轮廓将DAP无胶片转换为中心轴点剂量是可行的。然而,需要大量的轮廓(即准确的二维剂量重建需要15°增量(星型图案)),因此这种方法的水箱扫描可能会非常耗时。