Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Chemistry. 2019 Jan 28;25(6):1432-1435. doi: 10.1002/chem.201805359. Epub 2019 Jan 2.
A closed metallomolecular cage based on the tris(saloph) framework, in which its aperture can be opened by disulfide exchange, was designed. At the apertures of the molecular cage, bridging diamine ligands having a disulfide bond were introduced to close the cage structure. These bridging ligands efficiently blocked the uptake of a guest, Cs , but the presence of a thiolate anion significantly accelerated the guest uptake. This clearly means that this cage complex became open by the addition of the thiolate anion, because the cage closure becomes more dynamic due to the disulfide exchange reaction.
基于三（水杨醛）骨架设计了一种封闭的金属分子笼，其可以通过二硫键交换打开。在分子笼的孔口中，引入了具有二硫键的桥连二胺配体以关闭笼状结构。这些桥连配体有效地阻止了客体 Cs 的进入，但硫醇阴离子的存在显著加速了客体的进入。这清楚地表明，由于二硫键交换反应，这种笼状配合物变得开放，因为笼封闭由于二硫键交换反应而变得更加动态。
