Graduate School of Natural Science and Technology, Kanazawa University , Kakuma-machi, Kanazawa 920-1192, Japan.
Faculty of Pure and Applied Sciences, University of Tsukuba , 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan.
J Am Chem Soc. 2017 Apr 5;139(13):4631-4634. doi: 10.1021/jacs.7b00840. Epub 2017 Mar 24.
We designed a novel tricobalt(III) metallo-molecular cage in which its apertures can be closed with bifunctional ligands via coordination bonds. A closed-cage complex was easily formed by ligand exchange of its open-cage analogue. Guest uptake/release by the open-cage complex was sufficiently fast to quickly reach guest-binding equilibrium, while that by the closed-cage complex was extremely slow and took about 1 week to reach equilibrium. The guest uptake was retarded by at least 2000 times by introduction of the bifunctional ligands at the cage apertures.
我们设计了一种新型的三钴（III）金属分子笼，其孔穴可以通过配位键与双功能配体结合而关闭。通过其开口类似物的配体交换很容易形成封闭笼复合物。通过开口配合物的客体摄取/释放速度足够快，可以快速达到客体结合平衡，而通过封闭笼复合物的客体摄取/释放速度非常慢，需要大约 1 周才能达到平衡。通过在笼孔处引入双功能配体，客体摄取至少被延迟了 2000 倍。
