a Discipline of Paediatrics , Adelaide Medical School, University of Adelaide , Adelaide , South Australia , Australia.
b Robinson Research Institute , University of Adelaide , Adelaide , South Australia , Australia.
Hum Vaccin Immunother. 2019;15(4):951-958. doi: 10.1080/21645515.2018.1554966. Epub 2018 Dec 20.
To investigate the validity of parent reported influenza vaccination and provider reporting to the Australian Immunisation Register (AIR) in children with special risk medical conditions (SRMC).
Cross-sectional survey with parents of children with a SRMC aged ≥ 6 months and <18 years attending the Women's and Children's Hospital, Adelaide, Australia from September 2015 to February 2016. Children aged <7 years provided data to assess provider-AIR reporting. Influenza vaccination status was ascertained from the child's parent, immunisation provider and the AIR. Concordance was made using the Kappa index and the sensitivity, specificity, positive predictive value and negative predictive value were calculated.
389 and 395 parent-provider influenza vaccination records were available for 2014 and 2015 respectively. 78% of parent reported vaccinations were substantiated by a provider with the kappa indicating good (κ = 0.677) to very good agreement (κ = 0.814) for 2014 and 2015 respectively. Discordance was higher in 2014, largely attributable to parents over reporting vaccination. More fathers over reported compared to mothers (Fisher's exact = 0.052). There were 241 provider-AIR influenza vaccination records. Sensitivity of the AIR to reflect a child's influenza immunisation status was low (32.6%).
Parental report over estimates confirmed influenza vaccination status and is affected by time and relationship to the child. Only a third of influenza vaccinations were reported to the AIR. Timely accurate data is critical to facilitate vaccination and evaluate program coverage.
本研究旨在调查特殊风险医疗条件(SRMC)儿童父母报告的流感疫苗接种情况及其向澳大利亚免疫登记处(AIR)报告的有效性。
本研究采用横断面调查方法,于 2015 年 9 月至 2016 年 2 月,选取在澳大利亚阿德莱德妇女儿童医院就诊的≥6 月龄且<18 岁 SRMC 儿童的父母作为研究对象。<7 岁的儿童提供数据以评估提供者-AIR 报告。通过儿童的父母、免疫接种提供者和 AIR 确定流感疫苗接种状况。采用 Kappa 指数评估一致性,计算敏感性、特异性、阳性预测值和阴性预测值。
2014 年和 2015 年分别获得 389 份和 395 份父母-提供者流感疫苗接种记录。78%的父母报告的疫苗接种情况得到提供者的证实,2014 年和 2015 年的 Kappa 指数分别为 0.677(良好)和 0.814(非常好),表明具有较好的一致性。2014 年的不一致性更高,主要归因于父母过度报告疫苗接种情况。与母亲相比,更多的父亲过度报告疫苗接种情况(Fisher 确切检验,P = 0.052)。共有 241 份提供者-AIR 流感疫苗接种记录。AIR 反映儿童流感免疫接种状况的敏感性较低(32.6%)。
父母报告的流感疫苗接种情况过高,且受到时间和与儿童关系的影响。只有三分之一的流感疫苗接种情况向 AIR 报告。及时准确的数据对于促进疫苗接种和评估计划覆盖范围至关重要。