Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA; Clinical and Population Health Research Program, Graduate School of Biomedical Sciences, University of Massachusetts, Worcester, Massachusetts, USA.
J Pain Symptom Manage. 2019 Mar;57(3):535-544.e1. doi: 10.1016/j.jpainsymman.2018.11.023. Epub 2018 Dec 1.
Despite many nursing home residents experiencing pain, research about the multidimensional nature of nonmalignant pain in these residents is scant.
To identify and describe pain symptom subgroups and to evaluate whether subgroups differed by sex.
Using Minimum Data Set 3.0 data (2011-2012), we identified newly admitted nursing home residents reporting pain (n = 119,379). A latent class analysis included 13 indicators: markers for pain (i.e., severity, frequency, impacts sleep, and function) and depressive symptoms. Sex was evaluated as a grouping variable. Multinomial logistic models identified the association between latent class membership and covariates, including age and cognitive impairment.
Four latent subgroups were identified: severe (15.2%), moderate frequent (26.4%), moderate occasional with depressive symptoms (26.4%), and moderate occasional without depressive symptoms (32.0%). Measurement invariance by sex was ruled out. Depressed mood, sleep disturbances, and fatigue distinguished subgroups. Age ≥75 years was inversely associated with belonging to the severe, moderate frequent, or moderate occasional with depressive symptoms subgroups. Residents with severe cognitive impairment had reduced odds of membership in the severe pain subgroup (adjusted odds ratio [aOR]: 0.84; 95% confidence interval [CI]: 0.78-0.90) and moderate frequent pain subgroup (aOR: 0.60; 95% CI: 0.56-0.64) but increased odds in the moderate occasional pain with depressive symptoms subgroup (aOR: 1.12; 95% CI: 1.06-1.18).
Identifying subgroups of residents with different patterns of pain and depressive symptoms highlights the need to consider physical and psychological components of pain. Expanding knowledge about pain symptom subgroups may provide a promising avenue to improve pain management in nursing home residents.
尽管许多养老院居民都经历着疼痛,但关于这些居民中非恶性疼痛的多维性质的研究却很少。
确定和描述疼痛症状亚组,并评估亚组是否因性别而异。
使用最低数据集 3.0 数据(2011-2012 年),我们确定了报告疼痛的新入住养老院居民(n=119379)。一项潜在类别分析包括 13 个指标:疼痛标志物(即严重程度、频率、对睡眠和功能的影响)和抑郁症状。性别被评估为分组变量。多项逻辑回归模型确定了潜在类别成员资格与包括年龄和认知障碍在内的协变量之间的关联。
确定了四个潜在的亚组:严重(15.2%)、中度频繁(26.4%)、中度偶发伴抑郁症状(26.4%)和中度偶发无抑郁症状(32.0%)。排除了性别测量不变性。抑郁情绪、睡眠障碍和疲劳区分了亚组。年龄≥75 岁与属于严重、中度频繁或中度偶发伴抑郁症状亚组呈负相关。严重认知障碍的居民属于严重疼痛亚组(调整后比值比[aOR]:0.84;95%置信区间[CI]:0.78-0.90)和中度频繁疼痛亚组(aOR:0.60;95% CI:0.56-0.64)的可能性降低,但中度偶发性疼痛伴抑郁症状亚组的可能性增加(aOR:1.12;95% CI:1.06-1.18)。
确定具有不同疼痛和抑郁症状模式的居民亚组,突出了需要考虑疼痛的身体和心理成分。增加对疼痛症状亚组的了解可能为改善养老院居民的疼痛管理提供一个有前途的途径。