Department of Physical Education, Center of Health Sciences, State University of Maringa, Maringa, Brazil; Multidisciplinary Centre of Obesity Studies, State University of Maringa, Maringa, Brazil.
Multidisciplinary Centre of Obesity Studies, State University of Maringa, Maringa, Brazil.
Nutrition. 2019 Apr;60:19-24. doi: 10.1016/j.nut.2018.08.017. Epub 2018 Aug 27.
The aim of this study was to verify the prevalence of metabolically healthy obese (MHO) phenotype and associated factors in South American adolescents who are overweight.
A cross-sectional study was carried out with 340 overweight adolescent boys and girls between 10 and 18 y of age. The participants were classified as MHO according to two definitions: absence of any metabolic syndrome component and absence of insulin resistance (IR). The MHO phenotype-associated factors analyzed were age, sex, nutritional status, waist circumference (WC), body composition, metabolic profile, and cardiorespiratory fitness. Multivariable logistic regression was used to determine predictors of MHO using odds ratios with 95% confidence intervals.
The prevalence of MHO in South American overweight adolescents was 49.4% and 55.9% according to MS and IR criteria, respectively. Sex and WC were predictors of the MHO phenotype, considering MS classification criterion. For the IR criterion, age, WC, and triacylglycerol levels were independent predictors of MHO in adolescents. Cardiorespiratory fitness did not predict MHO phenotype in any of the criteria used.
The prevalence of MHO in South American overweight adolescents was high and varied according to the definition used. Age, sex, WC, and triacylglycerolslevel were independent predictors of the MHO phenotype in this population.
本研究旨在验证超重南美青少年中代谢健康肥胖（MHO）表型及其相关因素的流行情况。
本横断面研究纳入了 340 名 10 至 18 岁的超重青少年男女。根据两种定义将参与者分类为 MHO：无任何代谢综合征成分和无胰岛素抵抗（IR）。分析了与 MHO 表型相关的因素包括年龄、性别、营养状况、腰围（WC）、身体成分、代谢特征和心肺功能。使用比值比和 95%置信区间的多变量逻辑回归来确定 MHO 的预测因素。
根据 MS 和 IR 标准，南美超重青少年的 MHO 患病率分别为 49.4%和 55.9%。性别和 WC 是 MS 分类标准下 MHO 表型的预测因素。对于 IR 标准，年龄、WC 和三酰甘油水平是青少年 MHO 的独立预测因素。在使用的任何标准中，心肺功能都不能预测 MHO 表型。
南美超重青少年的 MHO 患病率较高，且根据使用的定义而有所不同。在该人群中，年龄、性别、WC 和三酰甘油水平是 MHO 表型的独立预测因素。
