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退行性变化在神经系统发育中的重要性:迈向儿童发育的神经生物学理论

The importance of regressive changes in the development of the nervous system: towards a neurobiological theory of child development.

作者信息

Carlson M, Earls F, Todd R D

机构信息

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110.

出版信息

Psychiatr Dev. 1988 Spring;6(1):1-22.

PMID:3050981
Abstract

In this paper we propose that theories of early personality development be revised to consider knowledge of neurodevelopment. Research findings are reviewed that have established the presence of regressive changes in the normal development of the brain. These regressive changes, consisting of neuronal death and process and synapse elimination, are theoretically linked to three precursors of personality: sex differences, temperamental traits and perceptual-motor coordination. Evidence supporting these hypotheses is provided from studies examining how the effects of genetic, environmental, and experiential factors on brain development may determine the development of these personality features.

摘要

在本文中,我们提议对早期人格发展理论进行修订,以纳入神经发育方面的知识。我们回顾了一些研究发现,这些发现证实了大脑正常发育过程中存在退行性变化。这些退行性变化包括神经元死亡、神经突和突触消除,从理论上讲,它们与人格的三个先兆有关:性别差异、气质特征和感知运动协调。通过研究遗传、环境和经验因素对大脑发育的影响如何可能决定这些人格特征的发展,为支持这些假设提供了证据。

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