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[In vitro movement of human embryonic fibroblasts with normal and anomalous sets of chromosomes].

作者信息

Freĭdin M I, Grinberg K N, Kaurov B A

出版信息

Tsitologiia. 1988 Jun;30(6):718-25.

PMID:3051604
Abstract

Migration of diploid postnatal and embryonic diploid and aneuploid cells was studied using a modified method of investigation of leukocyte migration under agarose. The method permits to study migration of fibroblasts and other proliferating cells. Embryonic fibroblasts were shown to move faster, than postnatal fibroblasts. Cells with trisomy 7, 9 and C, and triploid cells were found to move slower than diploid cells. Locomotor disturbances are supposed to be the basis of impairment of morphogenesis in chromosomal anomalies in man.

摘要

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